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BioWorld Science

Nov. 14, 2003

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PPARdelta shown to inhibit cardiac inflammatory responses in vitro and in vivo

Antiproliferative and differentiation-inducing effects of ratjadone on coronary smooth muscle cells

Antithrombotic efficacy of the PAR-1 antagonist E-5555 in guinea pigs

VX-702, a p38 MAPK inhibitor, reduces myocardial ischemia-reperfusion damage in rats

Amersham inlicenses amyloid-targeting PET agents

New uroselective alpha1-AR antagonists developed at Ranbaxy

Esteve scientists claim new NPY Y5 modulators for obesity and other uses

Pfizer presents two series of PPAR modulators with potential as antidiabetic agents

Novel estrogen receptor modulators prepared and tested by Wyeth researchers

CyFi patent covers sodium channel blockers as mucosa protecting agents

Lilly presents new factor Xa inhibitors

Orchid scientists present new COX-2/COX-3 inhibitors

New 5-HT1F agonists and their use in migraine therapy reported by Lilly

MRA potentially effective for adult rheumatoid arthritis

ICN becomes Valeant Pharmaceuticals International

Two additional pivotal trials for IGN-101

MK-0869 phase III program discontinued

New safety trial for HCV drug R-803

Preliminary phase Ib results support antiretroviral activity of TNX-355 for HIV

AIDSVAX B/E fails to meet endpoints in phase III HIV trial

Nitrate ester from GBTherapeutics improves cognition in rat model

YM BioSciences and Oncoscience sign licensing agreement for TheraCIM hR3

Erythropoietin and analogue AA-18231 afford significant neuroprotection in hypoxia-ischemia

Inhibition of glutamate carboxypeptidase II as a novel approach to diabetic retinopathy

Neuroprotective and antiinflammatory effects established for GLI-7501

Potent, rapid-acting antidepressant emerges from major Lundbeck program

Human central nervous system stem cell grafts improve recovery in SCI model

Human embryonic stem cell-derived oligodendrocyte progenitors: a promising approach to SCI

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