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BioWorld Science

Feb. 18, 2004

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Toll-like receptor 9 mediates beneficial effects of probiotics in vivo

Xenova studies selective MRP1 inhibitors for multidrug resistance in cancer

Cardioprotective effects of mitochondrial F1F0 ATPase hydrolase inhibitors described

Improved postprandial glycemia found with HIM2 in type 1 diabetes

Promising results found with topical doxycycline for chronic diabetic ulcers

Data on novel HIV-1 attachment inhibitor BMS-488043 presented in San Francisco

Myriad Genetics makes significant progress in advancing its product development strategy

Ariad highlights AP-23573 product development progress over past year

Human monoclonal antibody against SARS virus identified

Icos reports 2003 highlights

AxyS claims new caspase activators and their use in cancer and other disorders

Novel KDR inhibitors prepared and tested by Amgen researchers

Novel guanidine-based 5-HT6 receptor ligands presented by Wyeth

ARS team presents beta-sheet-breaking peptides for amylodogenesis-related disorders

AstraZeneca claims MCH-1R antagonists with potential as antiobesity agents

New orexin antagonists for obesity and sleep disorders in early development at Actelion

Axxima discovers casein kinase CKI inhibitors with utility in HCV infection

Fasgen and Johns Hopkins U. researchers claim agents for FAS, NPY and CPT-1-mediated disorders

Mucosal HIV-1 microbiocide delivery through bioengineered lactobacilli

aaiPharma receives approval for new methadone labeling

Rovicid supplement launched for cardiovascular health

Launch of Altovis supplement

Lilly completes acquisition of Applied Molecular Evolution

FDA accepts for review Riquent NDA

IND filing planned for ThromboView program

MEXT approval for Tanabe's project on use of human embryonic stem cells

Diagnostic Products Corporation nonexclusively acquires rights to NT-proBNP

Roche completes acquisition of Igen

Strong suppression of HBV replication found with emtricitabine in HIV-positive patients

In vitro metabolism and pharmacokinetics of the maturation inhibitor PA-457

Good pharmacokinetic profile found for IL-4/13 Trap in healthy volunteers

Strong antiviral effects of Sch-D monotherapy in HIV-infected patients

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