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BioWorld Science

March 30, 2004

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NeoGenesis and AstraZeneca enter R&D collaboration

Genesis Bioventures, Corgenix sign definitive merger agreement

STTR grant will support SARS vaccine efforts at Lipid Sciences

Evotec acquires NMDA receptor NR2B subtype selective antagonists from Roche

FibroGen research supports HIF activation technology for acute renal failure

Benefits reported for exemestane as first-line treatment for advanced breast cancer

Anastrozole improves the outcome of breast cancer surgery

Antiinflammatory effects of an oral aloe vera gel in patients with ulcerative colitis

Endothelin receptor antagonists for portal hypertension in cirrhosis

Treatment and prevention of dermal scars by procollagen C-proteinase inhibitor

Novel orally effective PAI-1 inhibitor for fibrinolytic dysfunction

Preliminary results from EMOTE study of enoximone for CHF

FDA requests additional Homspera mouse study

Positive European opinion for Lyrica

Clinical experience with Tumor Necrosis Therapy shared

Positive opinion handed down in Europe for duloxetine for SUI

OraQuick(R) Rapid HIV Antibody Test approved for use with oral fluid

Telzir receives positive opinion in Europe

Synaptic patent claims indolone derivatives for depression and anxiety

Novel inhibitors of alpha4 integrin-mediated cell adhesion for inflammatory diseases

Novel thrombin peptide derivatives disclosed in University of Texas patent

GlaxoSmithKline patent describes thiophene compounds as polo-like kinase 1 inhibitors

Antibacterial oxazolidinones under early development at Ranbaxy

Promising effects of rhC1INH in hereditary angioedema

Development of an anti-IL-6 monoclonal antibody for metastatic renal cell carcinoma

Good safety and pharmacokinetic profile of SRA-333 in healthy volunteers

Medac patent claims new use of treosulfan for MS

Use of CXCR5 receptor as target for diagnosis and treatment of cancer, cardiovascular diseases, etc.

Novel SARM for age-related muscle decline presented at ACS

Pharmacokinetic profile of lumiracoxib in Japanese subjects

Benefits of leptin replacement therapy in morbidly obese patients

Assessment of the effects of icatibant in healthy volunteers and cirrhotic patients

Insight into the mechanism of action behind antitumor activity of auraptene

AR6BD-25, a novel monoclonal antibody with anticancer activity

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