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BioWorld Science

March 8, 2005

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MPTP and calcium: novel targets for the treatment of Huntington's disease

SB-649915: Novel 5-HT1A receptor antagonist with potent 5-HT reuptake inhibitory activity

ATL-146e shows therapeutic benefit in a rabbit model of infectious arthritis

Insulin mimetic is an alternative therapeutic agent for diabetes

Yamanouchi synthesizes potent and orally active Factor Xa inhibitors

MJ-III-65 displays in vivo antitumor activity

Novel SARM effective in preclinical tests as hormonal male contraception / News in Context

Torcetrapib improves the lipid profile of patients with dyslipidemia

Pioglitazone identified as a potential treatment for ALS

Targeted gene disruption presented as a potential new HIV therapy

Meta-analysis of the efficacy of melatonin as a sleep aid

GPC Biotech acquires Axxima assets

Starpharma and Industrial Research establish glycodendrimer joint venture

Alliance and Leo amend Oxygent exclusivity agreement

Lenalidomide reported effective in multiple myeloma

Viral population changes found with AMD-3100 in HIV-infected patients

New data on the immunogenicity of the HIV vaccine EP HIV-1090

Varenicline reported to increase smoking cessation

In vitro evidence for an IGF-1R blocker, NVP-ADW-742, in the treatment of Ewing tumor

Three-month results from Progenta uterine fibroid study

Positive preliminary phase II data for Evizon in AMD

RNAi therapeutic shows potential for AMD in animal model

Alesion Dry Syrup approved for manufacturing in Japan

U.K. approval for phase I study of Reolysin in combination with radiation

Clarinex-D 24 Hour receives FDA approval

Femara receives new approval in Germany

Novel EDG1 (S1P1) receptor agonists developed by IRM

Theratechnologies disclose novel GLP-1 receptor ligands for diabetes

Heteroaryl prodrugs with antiviral/anticancer properties disclosed by Koronis

Novel matrix metalloproteinase (MMP) inhibitors prepared by GSK

Je Il researchers disclose tricyclic derivatives of colchicine for use in cancer therapy

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