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BioWorld Science

June 29, 2005

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Early studies reveal clinical activity of SOM-230

Novel PYY analogues CJC-1682 and CJC-1643 reduce food intake in rats

Chemically modified siRNAs are more effective against HBV in mice

YM-281956: A novel orally bioavailable NCX inhibitor

Aeras Global TB Vaccine Foundation supports Intercell and SSI project

deCODE updates recent progress

E1-INT studied in type 1 diabetics

Cholesterol-lowering drug FM-VP4 completes 90-day toxicity study

Metabasis and Merck collaborate in type 2 diabetes, hyperlipidemia and obesity

Sucampo suspends tacrolimus eye drops development program

Celtic Pharma recommended proposal to acquire Xenova

Phase I trial studies huC242-DM4 for cancer

Phase IIb study investigates APD-356 for obesity

Neose files IND for NE-180 for chemotherapy-induced anemia

KP-372-1 inhibits thyroid tumor cell proliferation

MX-2041 effective in pneumonia model

EW-A-401 studied for critical limb ischemia

GLP1-INT reverses hyperglycemia and evokes B-cell regeneration in vivo

LY-548806 shows promise as an i.v. treatment for hyperglycemia associated with critical illness

Salix to acquire InKine Pharmaceutical

SPA agreement on confirmatory phase III study for CP-226

In vitro and in vivo data support efficacy of exendin-4/lisofylline combination in type 1 diabetes

In vivo data presented on SX-004

New treatments for cancer covered in recent patents

Humira receives two new positive opinions in Europe

Xenical approved in Europe for use in adolescents

Novel agents imparted for immune and inflammatory disorders

Novel immunosuppressant agents disclosed by Novartis

Therapeutic benefits reported for apratastat in rheumatoid arthritis

Clinical trials confirm the efficacy of eszopiclone in sleep disorders

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