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BioWorld Science

Nov. 30, 2005

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Rats receiving CRF1 antagonist show reduction in submissive behavior

Ligand updates status of inhouse and partnered programs

Efficacy of LJ-529 in ER-negative breast cancer models

SPC-2968, an HIF-1 inhibitor, in preparation for initial clinical studies in 2006

Preclinical efficacy reported for GI-5005, a therapeutic vaccine for chronic hepatitis C infection

Enzon Pharmaceuticals and Micromet end research collaboration

European Commission approval for Teva's acquisition of Ivax

PharmaGap and OHSU Cancer Institute to collaborate on PKC inhibitors

GSK and Institut Pasteur collaborate to develop AIDS vaccine

American Pharmaceutical Partners to merge with American Bioscience

BioCryst submits IND for injectable formulations of peramivir

Enrollment completed in phase III study of Entereg in postoperative ileus

Phase III trials begin for PF-3512676 for NSCLC

Leo Pharma and Foamix to develop medicated foams for psoriasis

Agile completes phase II study for low estrogen contraceptive patch

Quadramet studied in combination with bortezomib for multiple myeloma

Neuren signs memorandum of understanding for Glypromate phase III trial

GW-610: new anticancer agent with potent and selective profile

New class of selective, orally active MEK1/2 inhibitors for cancer therapy

Feasibility of Syk kinase inhibition with R-406 demonstrated

Studies suggest benefit of IL-1 TRAP in atherosclerosis, CIAS1-associated syndromes

Ambrisentan beneficial in patients with connective tissue diseases and PAH

Obese, dyslipidemic subjects lose weight on rimonabant

Solvay suspends regulatory activities for cilansetron in U.S.

New antihepatitis C agents described in recent GSK patent

Novel agents for diabetes and related complications reported in recent patent literature

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