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BioWorld Science

April 23, 2008

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FDA requests review of clinical and preclinical safety data relating to IND for Heplisav

Sirtris reports results from phase Ib clinical trial of resveratrol for type 2 diabetes

Human Genome Sciences reacquires rights to mapatumumab and lexatumumab from GSK

Aastrom reports encouraging clinical results for autologous stem cell therapy

BMS-753493 cytotoxic in folate receptor-positive human tumor cells

Kosan demonstrates anticancer activity of CRM1-protein inhibition

SNS-314 induces tumor growth inhibition in xenograft models

AlphaVax announces initial results from phase I clinical trial of cytomegalovirus vaccine

Novel antimicrobial compounds imparted in recent patent literature

Motor improvement with pardoprunox in patients with early-stage PD seen in phase II trial

Clinical pharmacokinetic profile of XP-13512 reported at the AAN meeting

Mesoblast reports long-term results from animal trials of allogeneic stem cells for osteoarthritis

Kipres 5 mg tablets launched in Japan for bronchial asthma and allergic rhinitis

Amerge launched in Japan for migraine

Pfizer launches Revatio for PAH in Japan

Novel agents for treating urinary incontinence disclosed in recent Fujiyakuhin patent

Recent GSK and Peakdale patents describe new treatment options for endocrine-related disorders

Asahi Kasei receives approval for Famvir and signs marketing agreement with Maruho

Recordati submits NDA to FDA for Carbaglu for hyperammonemia due to NAGS deficiency

ARYx receives FDA clearance for phase I ATI-9242 trial

FDA grants orphan designation to ARC-1779 for the treatment of TTP

Initial studies in vivo with A3-APO show bactericidal activity

Immatics initiates phase I/II study of IMA-910 cancer vaccine in colorectal cancer

Lorus Therapeutics to examine new administration route for LOR-2040

Wyeth and Trubion commence phase I SBI-087 trial in rheumatoid arthritis

FDA approves Cimzia for the treatment of moderate to severe Crohn's disease

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