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BioWorld Science

Jan. 14, 2011

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Phase II data suggest fluoxetine improves motor recovery after ischemic stroke

Merck & Co. patents novel gamma-secretase modulators

Profectus BioSciences divulges new NF-kappa-B inhibitors

GSK discovers new lysophospholipid S1P1 receptor agonists

Vertex Pharma outlines its objectives for 2011

XL-184 receives FDA orphan drug status and is assigned generic name cabozantinib

Phase IIb trial evaluates budesonide as chemopreventive therapy in subjects with lung nodules

Cannabinoid CB1/CB2 receptors show promise as targets in NSCLC

PET ligand [11C]-RO-5013853 shows promise to evaluate Gly-T1 inhibitors

FDA accepts NDA for extended-release Janumet for review

Phase I ViaDerm-Calcitonin trial meets primary and secondary endpoints

Mithridion secures funding for drug development program

GSK-1605786 advances in phase III trial in Crohn's disease

Lilly presents new inhibitors of hedgehog signaling

FP-1097 is effective in phase II trial in female incontinence and overactive bladder

FDA accepts SmartRelief-Sumatriptan NDA for filing

Cephalon and Mesoblast report interim phase II data on Revascor

New histamine H3 receptor antagonists and/or inverse agonists discovered

Merck Serono claims new lysophospholipid S1P1 receptor agonists

FDA advisory committee recommends non-approval of Lilly's liprotamase NDA for EPI

Pfizer initiates rolling NDA submission for crizotinib for NSCLC

Enzon begins phase I study of EZN-4176 in castration-resistant prostate cancer

Daiichi Sankyo and ArQule initiate phase III trial of ARQ-197 in NSCLC

Shire reports study data on Vyvanse in excessive daytime sleepiness

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