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BioWorld Science

June 14, 2011

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OTS-11101 is well tolerated in first-in-human study in solid tumors

LY-2523355 advances in phase I trial in advanced/metastatic malignancies

Merck & Co. prepares novel adenosine A2A receptor antagonists

Genosco and Oscotec disclose new protein kinase inhibitors

Sirtris Pharmaceuticals presents new SIRT1 activators

Bristol-Myers Squibb patents new lysophospholipid S1P1 receptor agonists

EPI-743, a natural metabolite and orphan drug in inherited mitochondrial respiratory chain diseases

Metreleptin shows promise in partial lipodystrophy and amenorrhea

FDA accepts Adamis Pharmaceuticals' IND for APC-100 for prostate cancer

Phase I trial of Medicago's H1N1 flu vaccine shows safety and solid immune response

New putative biomarkers of systemic sclerosis identified

Bristol-Myers Squibb designs new series of HCV NS5A inhibitors

Scientists at Lilly describe novel opioid NOP receptor antagonists

Bionomics and Merck Serono extend MS collaboration

Forest Laboratories to launch Daliresp in U.S. this month

Two Morphotek products obtain FDA orphan drug status

FDA grants orphan drug status to Aradigm's ciprofloxacin for inhalation in bronchiectasis

Emergent BioSolutions' anthrax vaccine NuThrax gets FDA fast track status

First part of ivacaftor/VX-809 phase II trial in cystic fibrosis meets primary endpoints

Roche to make first milestone payment to Evolva in drug discovery collaboration

Synthes and Eli Lilly sign agreement focused on osteoporosis and bone fractures

Chugai provides update on application in Japan for Epogin in chemotherapy-induced anemia

Cell Therapeutics meets with FDA to discuss resubmission of pixantrone NDA

FDA approves Potiga as adjunctive treatment for partial-onset seizures

French and German authorities suspend use of pioglitazone-containing products

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