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BioWorld Science

May 16, 2019

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Buying time for therapy salvages lungs for transplant

Dynein axonemal heavy chain family identified as chemosensitivity-related genes in gastric cancer

Study confirms the oncogenic role of CDC20 in primary cutaneous squamous cell carcinoma

RPN2 as a biomarker to predict the outcome of chemotherapy for advanced gastric cancer

Small-molecule enhancers of E3 ligase-substrate interaction induce mutant beta-catenin degradation

A novel NOTCH3 mutation associated with epilepsy as an early manifestation of CADASIL

Surfactant protein D restricts HIV-1 passage across vaginal barrier in preclinical models

Tafazzin gene therapy created to treat Barth syndrome

InFlectis BioScience announces phase I results for IFB-088

Bispecific anti-VEGF/ANG-2 surrobody SL-634 shows potential to treat wet AMD

Vertex and Kymera enter strategic research and development collaboration

GABA-selective AAV therapy upregulates SCN1A to treat Dravet syndrome

New stroke therapy promotes motor recovery in mice

Bayer describes new P2X purinoceptor 3 antagonists

FORMA Therapeutics discloses new HDAC6 inhibitors

New phase I trial studies MK-8558 in antiretroviral-naive patients with HIV-1

FDA approves Venclexta with Gazyva for previously untreated CLL or SLL

FDA clears IND for Turning Point's TPX-0022

Emory University synthesizes fusion peptides including uPA or EGFR sequences with a toxin

Phase I/II results of DNase eye drops for dry eye disease

Vernalis, Servier present Bcl-2 inhibitors

New TrpC6 antagonists discovered by Hydra Biosciences and Boehringer Ingelheim

NCI studies whether Lixte's LB-100 can penetrate glioblastoma multiforme tumors

M.D. Anderson studies anti-PR1/HLA-A2 monoclonal antibody Hu8F4 in advanced hematologic malignancies