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BioWorld Science

April 15, 2020

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The next pandemic: fire breaks and host-directed therapies

Rejuvenating inflammation's end

Dose-expansion phase I data for trastuzumab deruxtecan in multiple advanced cancers

First-in-human data for telisotuzumab in advanced solid tumors

AstraZeneca initiates CALAVI study of Calquence against COVID-19

FDA approves IND application for GT-103

Moderna reports interim phase I data for mRNA-1893 vaccine

Positive topline phase I data reported for ADX-629

Sanofi and GSK collaborate to develop an adjuvanted vaccine for COVID-19

7 Hills Pharma cleared to conduct phase I study of 7HP349 in U.S.

Tocilizumab shows promise in single-center study in patients with COVID-19

Galectin-3 predicts prognosis in sudden cardiac arrest in out-of-hospital patients

Incyte discovers inhibitors of ALK2 and/or FGFR

New N-acetyl-beta-D-glucosaminidase inhibitors identified at Lilly

Fochon Pharmaceuticals, Shanghai Fochon Pharmaceutical patent RET inhibitors

New histamine H3 receptor antagonists identified at XW Laboratories

Suzhou Raymon Pharmaceuticals presents PI3K inhibitors

SP-8008 prevents thrombus formation without inducing bleeding by blocking vWF-GP Ib interaction

SST3-peptide agonists reduce nonfunctioning pituitary tumor cell viability and inhibit tumor growth

Upregulated serum markers identified in patients with LGE-negative DMD

Topoisomerase 2-beta knockdown yields model of diastolic dysfunction

Daiichi Sankyo studies DS-6157a for advanced GIST in first-in-human trial

Enrollment opens in phase I study of ALPN-202 for advanced malignancies

Oragenics reports early topline data from phase II study of AG-013 for oral mucositis

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