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BioWorld Science

May 20, 2020

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FDA authorizes IND application for MSC product for COVID-19-related ARDS

Antitumor activity seen with GPC3-CAR T-cell therapy in children with liver tumors

Subdividing and conquering PDAC

Phase II study of MGB-BP-3 in CDI meets primary endpoints

Vividion and Roche collaborate to discover and develop small molecules targeting E3 ligase

New in vivo data support prophylactic treatment potential of brilacidin against COVID-19

Covis Pharma initiates phase III study of Alvesco inhaler for the treatment of COVID-19

Soluble thrombomodulin as biomarker of severity in children with ARF

D-Dimer as a biomarker to predict mortality in patients with suspected pulmonary hypertension

ALS culprit TDP-43 affects synapses via CREB

Boehringer Ingelheim Pharma patents new ENPP2 inhibitors

Lundbeck presents Kv3 potassium channel activators

Theravance Biopharma identifies JAK inhibitors

Jiangsu Simcere Pharmaceutical synthesizes EGFR mutant inhibitors

New JAK1 inhibitors presented by Lynk Pharmaceuticals

Intrathecal GAN gene therapy appears safe in patients with giant axonal neuropathy

New oral multivalent vaccine candidate protects mice against H. pylori infection

Gene expression profile guiding personalized SMAC mimetic therapy in pediatric precursor B-cell ALL

Series of compounds against T. cruzi provides proof-of-concept efficacy in mice

Serum 14-3-3 protein gamma is a prognostic marker in IPF

Novavax studies SARS-CoV-2 recombinant spike protein nanoparticle vaccine in healthy subjects

Adjuvance receives NIAID funding to evaluate vaccine adjuvant with SARS-CoV2 antigen

Mini-dystrophin gene therapy PF-06939926 trial results boost phase III planning

FDA clears IND for phase II study of Atea's AT-527 for COVID-19

Aldeyra advances compounds with potential utility for COVID-19

FDA approves Lynparza for HRR gene-mutated castration-resistant prostate cancer

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