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BioWorld - Friday, March 29, 2024
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BioWorld Science
June 15, 2020
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PharmAbcine partners with Thermo Fisher to advance PMC-309
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New liver metastasis biomarker and target identified
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Y220X mutations impairing the thermostability of p53 can be targeted with small-molecule stabilizers
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Cullinan Oncology and PDI Therapeutics collaborate to develop CLN-619
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Macrophages rewire cholesterol metabolism for bacterial toxin defense
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Optimized tandem CD19/CD20 CAR-engineered T cells induce durable antitumor response
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First-in-human data for FP-1305
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Boehringer Ingelheim reveals phase I data for BI-836880 plus BI-754091 in NSCLC
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Janus kinase inhibitors patented by Jiangsu Hansoh Pharmaceutical, Shanghai Hansoh Biomedical
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Yangtze River Pharmaceutical, Shanghai Haiyan Pharmaceutical Technology describe IDO-1 inhibitors
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RORC antagonists presented by Jiangsu Chia Tai Tianqing Pharmaceutical, Nanjing Gear Pharma & Tech
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Harvard College and Zikani Therapeutics identify new azaketolides
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Roche presents DNA gyrase and/or DNA topoisomerase IV inhibitors
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MDM2 inhibitor KRT-232 shows promise in phase II study in myelofibrosis patients
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Initial phase I data show promise for PKCbeta inhibitor MS-553 in R/R CLL/SLL
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Sinovac releases preliminary phase I/II results for CoronaVac
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ILT-101 expands and activates regulatory T cells in autoimmune/inflammatory diseases
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Seattle Genetics opens enrollment in phase I study of SGN-B6A for advanced solid tumors
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Carsgen initiates phase I study of AB-011 in CLDN18.2-positive advanced solid tumors
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New phase I study of KRAS peptide vaccine in colorectal and pancreatic cancer
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Zai Lab studies anti-CD47 antibody ZL-1201 for advanced cancer in phase I
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FDA approves dispersible tablet formulation of dolutegravir for infants and children with HIV
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Novartis studies MAS-825 in phase II for COVID-19
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FDA approves Gardasil 9 for HPV-related oropharyngeal and head and neck cancers
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