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BioWorld Science

Jan. 27, 2021

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Tetracyclines may help in mitochondrial disease

BioVaxys announces advances in its vaccine platforms

TLR2/6 activation using INNA-051 shows promise as prophylactic strategy against COVID-19

Model reveals key role of LGI1-ADAM22-MAGUK complex in transsynaptic nanoarchitecture

Enrollment begins in first-in-human trial of BI-1808 in solid tumors and CTCL

Vir releases initial phase I data for its HBV-neutralizing monoclonal antibody, VIR-3434

Keytruda approved in Europe as first-line treatment of metastatic MSI-H or dMMR colorectal cancer

First patients dosed in phase II study of GS-248 in systemic sclerosis

Incyte divulges FGFR-3 inhibitors

Medshine Discovery patents new PORCN inhibitors

Positive interim data from phase III prevention trial of REGEN-COV

Boragen presents new tyrosine kinase inhibitors

Qilu Regor Therapeutics patent details MAP4K1 inhibitors

New CDK inhibitors patented by Nuvation Bio

Microbial tyrosine metabolism protects against asthma

BLAZE-1 study of bamlanivimab plus etesevimab meets primary endpoint in high-risk COVID-19

OS Therapies receives approval for its phase IIb study of OST-HER2 in osteosarcoma

PARP inhibitor stenoparib shows activity against SARS-CoV-2

Rhythm presents positive clinical data and development update for setmelanotide

FDA approves phase II/III HIBISCUS trial of traumakine in patients with COVID-19

FDA allows Cardif Oncology to proceed with phase II trial of onvansertib in PDAC

Sorrento reports preliminary phase Ib results on COVI-MSC for COVID-19

Primary endpoint met in ACTIVATE-T trial of mitapivat in transfused patients with PK deficiency

Syndesi reports phase I data on SV2A modulator SDI-118

DPP-4 inhibitor sitagliptin prevents incidence of GvHD after allogeneic HSCT in AML

BriaCell reports data from monotherapy and combination therapy studies of Bria-IMT

FDA clears IND for anti-4-1BB therapeutic monoclonal antibody EU-101

NIAID reports phase IIb results on VRC-01 for HIV prevention

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