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BioWorld Science

July 15, 2021

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New carboxylic acids synthesized at Prometic Pharma SMT

Mutant EGFR inhibitors identified at Roche

Merck & Co. discovers protein arginine N-methyltransferase 5 inhibitors

New G12C mutant GTPase KRAS inhibitors presented by Novartis

NRx partners with IIBR to develop and commercialize BriLife COVID vaccine

MASP-2 levels tied to asthma severity

DoD award supports Evrys Bio's development of drug against multiple high-risk viruses

Enrollment opens in first-in-human study of VIB-1116 for rheumatic diseases

LAVA begins dosing in phase I/IIa study of LAVA-051 in hematological malignancies

New model of prosthetic joint infection allows assessment of new treatment options

Complement system alternative pathway linked to worse outcome in hospitalized COVID-19 patients

MicroRNAs identified as markers of response to benralizumab treatment

HT-003 reduces expression of inflammatory cytokines in acne therapeutic model

Qualigen submits IND application for QN-165 for the treatment of COVID-19

Revalesio initiates phase II study of RNS-60 in acute ischemic stroke

DDX21 has prognostic impact in adrenocortical carcinoma

Enrollment begins in phase I study of BI-1810631 in advanced solid tumors

CIHR grant supports Arch's evaluation of LSALT in chronic kidney and lung diseases

Adial reports preclinical data with adenosine analogues for pain

Discovery of novel siderophore-monobactam conjugates against P. Aeruginosa

Antibiotics double as antitumor kinase inhibitors

Escient reports phase I data on EP-547 for pruritus associated with cholestasis and uremia

Dosing commences in phase II study of STP-705 for keloid scar prevention

FDA lifts partial clinical hold on phase Ib study of RVU-120 in AML and MDS

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