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BioWorld - Wednesday, June 7, 2023

Gastrointestinal

Home » Topics » Disease categories and therapies » Gastrointestinal
  • Pancreas1
    June 7, 2023

    CM-5480 protects acinar and ductal functions, prevents progression of chronic pancreatitis

    The pathogenesis of chronic pancreatitis (CP) is complex and involves interactions among different cell types, including pancreatic acinar, ductal and stellate cells (PSC). Researchers from Calcimedica Inc. and the University of Szeged set out to assess the pathogenic pathways in these cells as well as evaluate the potential of the novel calcium release-activated calcium channel protein 1 (Orai1) inhibitor CM-5480 as a potential treatment for CP.
  • June 7, 2023

    Onquality’s CDK4/6 inhibitor cleared to enter clinic for chemotherapy-induced diarrhea

    Onquality Pharmaceuticals LLC has received FDA clearance of its IND application for OQL-051 for the prophylaxis of chemotherapy-induced diarrhea.
  • June 6, 2023
    By Doris Yu

    Canbridge obtains first approval for Alagille syndrome in China

    Canbridge Pharmaceuticals Inc. obtained marketing approval from China’s NMPA for CAN-108 (Livmarli; maralixibat chloride oral solution) to treat cholestatic pruritus in 1-year-old or older patients with Alagille syndrome, a development that the company touted for how quickly it followed similar approvals elsewhere.
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