DUBLIN – By the end of the year, Adrenomed AG will have a pretty good idea whether its lead drug candidate, adrecizumab, is a runner in what is one of the most challenging of all indications. A phase II trial of the drug in patients with early septic shock has already passed an interim efficacy analysis in half of the 300 patients the study is enrolling. The company aims to complete the study this year – and it could then be in a position to contemplate applying for conditional marketing authorization in Europe.