The 21st Century Cures Act may eventually set a new legislative land speed record for conception to passage in the House of Representatives, but the bill nonetheless reintroduces interested parties to an issue as old as budgets themselves. The bill would forward roughly $550 million to the FDA for its share of the Cures lift, but the agency estimates that its share of the work might cost a bit more than $958 million, leaving the FDA with a $400 million-plus hole to fill should the bill be signed into law.