• Curis Inc., of Lexington, Mass., and Genentech Inc., of South San Francisco, a member of the Roche Group, said the FDA accepted and filed the new drug application (NDA) for vismodegib, a Hedgehog pathway inhibitor, for use in adults with advanced basal cell carcinoma (BCC) for whom surgery is considered inappropriate. The application was granted priority review status, with a PDUFA date of March 8, 2012.