| I. MODIFIED AGREEMENTS | |||
| Biotech Co.* (Country; Symbol) |
Pharma Co. (Country) |
Change from original agreement |
Terms/Details (Date) |
|
Memory Pharmaceuticals Corp. (MEMY) |
F. Hoffmann-La Roche Ltd. (Switzerland) | Roche maintained its option to exclusively license MEM 3454 for treating neurological disorders | The move followed Phase I work that resulted in a $2M milestone payment to Memory; Roche's option remains through Phase IIa trials (10/31) |
| II. TERMINATED AGREEMENTS | |||
|
CV Therapeutics Inc. (CVTX) |
Solvay Pharmaceuticals Inc. | CV is terminating the co-promotion agreement for Aceon | The deal on the angiotensin-converting enzyme inhibitor was to have run through 2010; no payments are due under the termination (10/11) |
| Novacea Inc.(NOVC) | Pierre Fabre Medicament SA (France) | Novacea is returning to Pierre Fabre the U.S. and Canadian rights to oral vinorelbine | Novacea licensed the cancer product in 2005; it was notified by the FDA that the development path would be longer than anticipated (11/1) |
| Notes: | |||
| # The information in the chart does not cover agreements between biotech companies or agricultural agreements. | |||
| * Private companies are indicated with an asterisk. | |||
| Unless otherwise noted, stock symbols listed are on the Nasdaq market. | |||
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