I. MODIFIED AGREEMENTS

Biotech Co.*
(Country;
Symbol)

Pharma Co.
(Country)

Change from original
agreement

Terms/Details (Date)


Ariad
Pharmaceuticals
Inc.
(ARIA)

Eli Lilly and Co.

A District Court jury ruled Lilly's Evista and Xigris drugs infringed Ariad patents on treating disease by regulating NF-(kappa)B cell-signaling

Ariad was awarded damages of $65.2M, representing a royalty rate of 2.3% and said it would get 2.3% of U.S. sales of the drugs through 2019; Lilly plans to challenge the verdict (5/4)

Cytogen Corp.
(CYTO)

Berlex Inc.

Cytogen bought out Berlex's royalty interest in Quadramet, an approved oncology product

Berlex gets a payment of $6M and 623,441 Cytogen shares that were valued at about $2M; it also could get about $8.35M in sales-based milestone payments (5/8)


Notes:

# The information in the chart does not cover agreements between biotech companies or agricultural agreements.

* Private companies are indicated with an asterisk.

Unless otherwise noted, stock symbols listed are on the Nasdaq market.

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