Company

Offering Month

Offering Price

97 Close

Percentage

Progenitor Inc.

Aug.

5.375

2.375

-56

ArQule Inc.

April

12

22.94

91

PathoGenesis Corp.

March

27

37.13

38

SangStat Medical Corp.

March

30

40.5

35

Incyte Pharmaceuticals Inc.

July

67

45

34

Anika Therapeutics Inc.

Nov.

7

9.31

33

Coulter Pharmaceuticals Inc.

Oct.

15.5

20.25

31

Epix Medical Inc.

Nov.

10

13

30

ViroPharma Inc.

July

13.75

17.63

28

Protein Design Labs Inc.

March

32

40

25

Texas Biotechnology Corp.

Sept.

5

6.19

24

Quintiles Trans national Corp.

March

62.88

38.25

22

Cor Therapeutics Inc.

Oct.

19

22.5

18

Cellegy Pharmaceuticals Inc.

Nov.

7.5

8.38

12

Human Genome Sciences Inc.

March

37

39.75

7

Maxim Pharmaceuticals Inc.

Oct.

15.25

16.38

7

Cell Therapeutics Inc.

Oct.

16

17

6

Inhale Therapeutic Systems

Oct.

24.88

26

5

LifeCell Corp.

Nov.

4.5

4.63

3

Aviron

Aug.

27

27.13

0

CollaGenex Pharmaceuticals Inc.

April

12.5

12.5

0

Guilford Pharmaceuticals Inc.

April

20

20.13

0

Magainin Pharmaceuticals Inc.

Nov.

8

8.06

0

Synsorb Biotech Inc.

July

C$7.75

C$7.70

0

Emisphere Technologies Inc.

July

19

18.63

-2

Celgene Corp.

Nov.

9

8.44

-6

Genzyme Tissue Repair

Nov.

7.75

6.88

-11

Digene Corp.

Oct.

10

8.63

-14

Synaptic Pharmaceutical Corp.

Oct.

12.63

10.88

-14

Sugen Inc.

Nov.

16

13.13

-18

Vertex Pharmaceuticals Inc.

March

45.5

33

-27

Genetronics Biomedical Ltd.

June

C$4.30

C$3.09

-28

Zonagen Inc.

July

30

18.19

-40

Oxis International Inc.

May

0.8

0.42

-47

Vanguard Medica Group plc

Dec.

12.15

4.24

-65

Cambridge Neuro-Science Inc.

Jan.

11

1.97

-82