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BioWorld - Sunday, February 1, 2026
Home » chronic lymphocytic leukemia

Articles Tagged with ''chronic lymphocytic leukemia''

Head to head: Beigene’s BTK inhibitor yields solid data against Imbruvica

April 28, 2021
By Lee Landenberger
Beigene Ltd.’s selective inhibitor, Brukinsa (zanubrutinib), made up for a 2019 miss in a head-to-head study against Johnson & Johnson and Abbvie Inc.’s Imbruvica (ibrutinib) with positive new data from a phase III trial in adults with relapsed or refractory chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma.
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Ascentage’s New Year’s resolution includes getting its first candidate to market

Jan. 12, 2021
By Gina Lee
HONG KONG – Tapping into synergies it sees between the U.S. and Chinese biotech industries, Suzhou, China-based Ascentage Pharma Group International is aiming to get its most advanced candidate, HQP-1351, to market this year.
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Ascentage’s New Year’s resolution includes getting its first candidate to market

Jan. 11, 2021
By Gina Lee
HONG KONG – Tapping into synergies it sees between the U.S. and Chinese biotech industries, Suzhou, China-based Ascentage Pharma Group Corp. Ltd. is aiming to get its most advanced candidate, HQP-1351 (olverembatinib dimesylate) to market this year for patients with TKI-resistant chronic myeloid leukemia.
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Ascentage co-develops Bcl-2 and BTK combination therapy for SLL/CLL with Astrazeneca

June 23, 2020
By Elise Mak
BEIJING – Suzhou, China-based Ascentage Pharma Group Inc. said on June 22 that it is working with Astrazeneca plc’s hematology R&D unit, Acerta Pharma, to develop a combination therapy of its Bcl-2 inhibitor, APG-2575, with Acerta's BTK inhibitor, Calquence (acalabrutinib). The first patient has been dosed in the U.S.
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Ascentage co-develops Bcl-2 and BTK combination therapy for SLL/CLL with Astrazeneca

June 22, 2020
By Elise Mak
BEIJING – Suzhou, China-based Ascentage Pharma Group Inc. said on Monday that it is working with Astrazeneca plc’s hematology R&D unit, Acerta Pharma, to develop a combination therapy of its Bcl-2 inhibitor, APG-2575, with Acerta's BTK inhibitor, Calquence (acalabrutinib). The first patient has been dosed in the U.S.
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Leukemia illustration
The umbralisib and ublituximab band

TG Therapeutics sings U2 interim success in CLL

May 5, 2020
By Brian Orelli
TG Therapeutics Inc. got a dose of good news when the independent data safety monitoring board recommended that the UNITY-CLL study be stopped early for superior efficacy after an interim analysis showed its umbralisib and ublituximab combination (U2) helped patients with chronic lymphocytic leukemia (CLL).
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ASH 2019

Janssen’s Imbruvica improves survivability

Dec. 9, 2019
By Lee Landenberger
ORLANDO, Fla. – Not long past the opening of the American Society of Hematology’s (ASH) massive annual conference, Janssen Biotech Inc. released upbeat follow-up survivability data on Imbruvica (ibrutinib) from two studies and an integrated analysis evaluating Imbruvica in previously untreated patients with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL).
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