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Home » brain map

Articles Tagged with ''brain map''

Silhouette of head and brain with DNA double helixes
Neurology/psychiatric

Armamentarium, the new genetic weapon to study brain disorders

May 22, 2025
By Mar de Miguel
No Comments
A collaboration of scientists from the NIH Brain Initiative consortium has published eight simultaneous studies in Neuron, Cell, Cell Genomics, Cell Reports and Cell Reports Methods, with the results of the Armamentarium project, a new set of gene therapy tools for the research and treatment of human brain disorders. The methodology, based on genetic techniques, RNA detection, genomic enhancers and viral vectors, is designed to access different CNS cell types, neuronal and non-neuronal cells, with common and reproducible protocols now available for any laboratory.
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Colorful illustration of reconstructed brain cells
Neurology/psychiatric

Mouse brain structure and function shown on high-resolution map

April 11, 2025
By Mar de Miguel
Scientists from the Machine Intelligence from Cortical Networks (MICRONS) consortium have published the microconnectome of a cubic millimeter of the mouse brain. This is the most complete map of this organ to date at nanometer resolution for a mammal. It not only contains the structure and connections of each and every cell in that volume of tissue, but is also linked to the neuronal activity of that portion of the CNS, linking anatomy and function in the same cells.
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Tanycytes illuminated and color coded according to their depth in the hypothalamus brain of a mouse
Aging

Map is first step toward healthy brains into old age

Jan. 14, 2025
By Anette Breindl
2024 saw the completion of several cellular-resolution brain maps, including the entire fly brain and a comprehensive connections map of a cubic centimeter of human brain. 2025 began with the addition of another important map. In the Jan. 1, 2025, issue of Nature, researchers from the Allen Institute presented a map of areas and cell types where aging most affected the mouse brain.
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Tanycytes illuminated and color coded according to their depth in the hypothalamus brain of a mouse
Aging

Map is first step toward healthy brains into old age

Jan. 9, 2025
By Anette Breindl
2024 saw the completion of several cellular-resolution brain maps, including the entire fly brain and a comprehensive connections map of a cubic centimeter of human brain. 2025 began with the addition of another important map. In the Jan. 1, 2025, issue of Nature, researchers from the Allen Institute presented a map of areas and cell types where aging most affected the mouse brain.
Read More
Video still showing the brain inside an adult fruit fly

The map for a journey to the center of the brain

Dec. 27, 2024
By Mar de Miguel
In the 1970s, scientists from several countries proposed to reconstruct, one by one, all the neurons in the brain as they appear under an electron microscope. They started with a small worm. Caenorhabditis elegans has only 302 neurons. It took 16 years. How much time would be required to repeat this arduous task for the 100 billion neurons in the human brain?
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Video still showing the brain inside an adult fruit fly

The map for a journey to the center of the brain

Dec. 24, 2024
By Mar de Miguel
In the 1970s, scientists from several countries proposed to reconstruct, one by one, all the neurons in the brain as they appear under an electron microscope. They started with a small worm. Caenorhabditis elegans has only 302 neurons. It took 16 years. How much time would be required to repeat this arduous task for the 100 billion neurons in the human brain?
Read More
Video still showing the brain inside an adult fruit fly
Neurology/psychiatric

The map for a journey to the center of the brain

Dec. 23, 2024
By Mar de Miguel
In the 1970s, scientists from several countries proposed to reconstruct, one by one, all the neurons in the brain as they appear under an electron microscope. They started with a small worm. Caenorhabditis elegans has only 302 neurons. It took 16 years. How much time would be required to repeat this arduous task for the 100 billion neurons in the human brain?
Read More
Adult fly brain 3D reconstruction
Neurology/psychiatric

140,000 cells and 50M synapses make 1 adult fly brain

Oct. 3, 2024
By Mar de Miguel
A collaboration led by the Flywire Consortium and comprising hundreds of scientists has completed a whole map of the adult fruit fly brain after several decades of collaborative work.
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Adult fly brain 3D reconstruction
Neurology/psychiatric

140,000 cells and 50M synapses make 1 adult fly brain

Oct. 2, 2024
By Mar de Miguel
A collaboration led by the Flywire Consortium and comprising hundreds of scientists has completed a whole map of the adult fruit fly brain after several decades of collaborative work. By using electron microscopy and three-dimensional reconstruction supported by AI tools, the researchers have revealed the neural wiring of the Drosophila melanogaster brain, a connectome of 140,000 neurons with 50 million synaptic connections. In the future, researchers could possibly use this map as an artificial in silico model to study the brain as a simulator through its connections, though a lot of work remains to be done for this.
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Brain and DNA

Brain cell maps, the neurological zoom of psychiatric disorders

May 30, 2024
By Mar de Miguel
Understanding psychiatric disorders at a cellular and molecular level could provide a different perspective to design diagnostic and therapeutic tools searching for the origin of these disorders and the alterations they cause. Fourteen simultaneous studies from the PsychENCODE Consortium have delved into the cellular atlases of human neurodevelopment, reporting the broadest view of neuropsychiatry to date.
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