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Home » Topics » Science » Cell therapy

Cell therapy
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Illustration of cancer cells and immunotherapy treatment
Immuno-oncology

Medigene selects clinical indications for TCR-T therapy

Feb. 13, 2024
Medigene AG has selected initial clinical indications for its lead candidate, MDG-1015, specifically gastric cancer, ovarian cancer, myxoid/round cell liposarcoma and synovial sarcoma.
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3D illustration of T cells fighting cancer
Immuno-oncology

Acepodia’s allogeneic γδ2 T-cell therapy for EGFR-expressing solid tumors cleared to enter clinic

Feb. 5, 2024
Acepodia Inc. has obtained FDA clearance of its IND application for ACE-2016, an allogeneic γδ2 T-cell therapy for the treatment of epidermal growth factor receptor (EGFR)-expressing malignancies in patients with solid tumors.
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Immuno-oncology

Combining AMP vaccination with TCR T-cell therapies leads to improved and durable antitumor efficacy

Feb. 1, 2024
Amphiphile (AMP)-modification of peptide antigens and molecular adjuvants has been previously demonstrated to enhance lymphatic delivery and retention, resulting in potent expansion of cognate endogenous T-cell responses.
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Close-up of eye with digital focus
Ocular

Bluerock exercises option to primary photoreceptor diseases iPSC

Jan. 26, 2024
Bluerock Therapeutics LP, a wholly owned, independently operated subsidiary of Bayer AG, has exercised its option to exclusively license OpCT-001, an induced pluripotent stem cell (iPSC) derived cell therapy candidate for the treatment of primary photoreceptor diseases, from Fujifilm Cellular Dynamics Inc. and Opsis Therapeutics LLC.
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3d illustration of ovarian cancer
Immuno-oncology

NK Celltech announces US IND clearance for NK cell therapy NK-010

Jan. 23, 2024
NK Celltech Co. Ltd. has announced FDA clearance for a clinical trial of NK-010, a nongenetically modified allogeneic peripheral blood natural killer (NK) cell drug.
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Immune

Tr1x series A to advance allogeneic cell therapies

Jan. 18, 2024
Tr1x Inc. announced a $75 million series A financing to advance universal allogeneic regulatory T (Treg) and chimeric antigen receptor (CAR)-Treg cell therapies into the clinic to treat autoimmune and inflammatory diseases.
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Gene editing illustration
Neurology/Psychiatric

DoD grant supports Factor Bioscience's development of gene-edited cell therapies

Jan. 12, 2024
Factor Bioscience Inc. has been awarded a grant by the U.S. Department of Defense to develop next-generation cell therapy candidates using Factor's patented mRNA, cell-reprogramming, and gene-editing technologies.
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Handshake with DNA, molecules
Immuno-oncology

Iaso, Umoja collaborate on cell and gene therapies

Jan. 4, 2024
Iaso Biotherapeutics Co. Ltd. has established new collaborations with Umoja Biopharma Inc. for the development and commercialization of novel ex vivo and in vivo cell and gene therapies. These collaborations seek to advance off-the-shelf cell and gene therapies with applications in oncology and immunology.
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Photomicrograph of bone marrow aspirate showing myeloblasts of acute myeloid leukemia
Cancer

FDA clears Senti Biosciences’ IND for SENTI-202

Dec. 27, 2023
Senti Biosciences Inc. has received clearance of its IND application from the FDA for SENTI-202, an off-the-shelf chimeric antigen receptor natural killer (CAR-NK) cell therapy product candidate designed to selectively target and eliminate CD33- and/or FLT3-expressing hematologic malignancies, such as acute myeloid leukemia (AML) and myelodysplastic syndrome, while sparing healthy bone marrow cells.
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T cells attacking cancer cells
Immuno-oncology

Immunoscape and Mink collaborate on next-generation TCR therapies

Dec. 21, 2023
Immunoscape Pte Ltd. and Mink Therapeutics Inc. have entered into a collaboration agreement to discover and develop next-generation T-cell receptor (TCR) therapies against novel targets in solid tumors.
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