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Home » Topics » Science » Organoids

Organoids
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Diagram comparing healthy heart organoid to post-heart attack organoid

Human heart organoids provide unmatched insight into cardiac disease and dysfunction

Oct. 12, 2020
By Annette Boyle
Two teams of researchers have developed miniature models of the human heart that beat and function like the full-size organ. The team from Michigan State University (MSU) and Washington University in St. Louis developed a human heart organoid (hHO) that recapitulates embryonic heart development, providing an unmatched view into congenital heart defects. The organoid created by the researchers at the Medical University of South Carolina (MUSC) and Clemson University mimics the tissue dysfunction that occurs following a heart attack.
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Brain with puzzle piece removed

Down syndrome organoids give insights into Alzheimer’s disease

July 17, 2020
By Nuala Moran
LONDON – New human brain organoids that precisely model the three hallmarks of Alzheimer’s disease – amyloid plaque-like lesions, progressive neuronal death and abnormal accumulations of tau – are now ready to be developed for use in high-throughput drug screening.
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Stem cell-derived cerebral organoid
ISSCR 2020

‘Hope, hype and hubris’ of brain organoids on display at stem cell meeting

June 26, 2020
By Anette Breindl
Technical challenges at the annual meeting of the International Society for Stem Cell Research (ISSCR) meeting led to at least one lively exchange of stem cell jokes in the chat box as the audience waited for talks to resume, including stem cell parental advice: “You can be anything you want when you grow up!”
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Coins, stock chart illustration

Three of a perfect pair: Volastra launches with a $12M financing

Feb. 11, 2020
By Lee Landenberger
The three founders of newly launched Volastra Therapeutics Inc. had plenty in common when they decided to create the company. Their offices happened to be a half block apart on 69th Street in midtown Manhattan. Their interests in oncology were similar but each approached the disease from different angles.
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Brain organoids
‘Confused and disorganized’

Stress, identity crises part of growing up – for organoids

Jan. 29, 2020
By Anette Breindl
When developmental neurobiologist Arnold Kriegstein talks about his work, it sounds for all the world like he is talking about the brains of teenagers. They are stressed. Their identity is mixed up. But putting them in a good environment is helpful to their development. Kriegstein, though, was describing brain organoids.
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