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Home » Topics » Science » Organoids

Organoids
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Colon cancer illustration
Cancer

Intron demonstrates inhibition of tumorigenesis using P18-BE3CRC in colorectal cancer organoid model

April 4, 2023
Intron Biotechnology Inc. has demonstrated the effectiveness of P18-BE3CRC using a cancer organoid model.
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Intestine
Gastrointestinal

Collplant, Tel Aviv University and Sheba Medical Center collaborate on gut-on-a-chip tissue model

Nov. 16, 2022
Collplant Biotechnologies Ltd. and Ramot at Tel Aviv University Ltd., the technology transfer company of Tel Aviv University and Sheba Medical Center, have entered into a license and research agreement to codevelop a gut-on-a-chip tissue model for drug discovery and high-throughput screening of drugs.
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Cancer

Unravel Biosciences and Spanios partner to discover therapeutic targets for rare cancers

Nov. 10, 2022
Unravel Biosciences Inc. has entered into a partnership with Spanios to discover therapeutic targets for rare cancers.
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Neurology/Psychiatric

Transplanted human cortical organoids integrate anatomically and functionally into the rodent brain

Nov. 3, 2022
Self-organizing organoids resembling specific regions of the nervous system, including human cortical organoids (hCO), can be generated and used as disease models. However, the application of hCOs is precluded by several limitations, including the lack of integration into in vivo circuits that generate behavioral outputs. To overcome these issues, transplantation of hCOs into intact living brains has been proposed.
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Lung cancer illustration
Cancer

Sengine Precision seeks to identify novel therapeutic targets in progressive ALK+ NSCLC

Sep. 29, 2022
Sengine Precision Medicine Inc. is conducting a study utilizing its high-throughput patient-derived organoid drug screening technology to identify novel therapeutic targets in progressive anaplastic lymphoma kinase (ALK)-positive non-small-cell lung cancer (NSCLC).
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Liver organoid
Drug Design, Drug Delivery & Technologies

Emulate launches new AAV transduction application for Liver-Chip

Sep. 20, 2022
Emulate Inc. has launched a new adeno-associated virus (AAV) transduction application for the Liver-Chip that enables gene therapy researchers to test the delivery efficiency and safety of AAV vectors in a validated, human-relevant model of the liver and get results in weeks.
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3D dollar sign

Sengine nearly quadruples funding with $15M series A to advance organoid-based testing

Aug. 8, 2022
By Annette Boyle
Sengine Precision Medicine Inc. boosted its total fundraising to $19 million with the recent closing of a $10 million series A2 led by the Washington Research Foundation with support from Alethea Fulcrum Fund, Vincere Capital Biotech LLC, Bangarang Group and others. The A2 follows on an earlier $5 million raised in the original series A. Sengine’s Paris Test predicts drug responses using a patient’s cancer cells to grow a tumor organoid that replicates the functionality and genomic characteristics of the original tumor, enabling hyper-personalization of cancer treatment.
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Dollar sign in light bulb on yellow background

Xilis lands $19M series A extension for microorganosphere platform

July 14, 2022
By Catherine Longworth
Xilis Inc. added $19 million to its series A financing round, bringing the total amount raised to over $89 million. FPV Ventures led the extension, with participation from Alexandria Venture Investments and EQT Life Sciences, Mubadala Capital Management, Pear Ventures, GV, the Duke Angel Network, Catalio Capital Management, Two Sigma Ventures, Felicis Ventures and Alix Ventures.
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Kidneys

Three components enable 3D kidney tissue from mouse embryonic stem cells

Feb. 8, 2022
By Tamra Sami
Japanese researchers have created complex 3D kidney organoids that could lead the way to better kidney research and even artificial kidneys for human transplant.
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Diagram comparing healthy heart organoid to post-heart attack organoid

Human heart organoids provide unmatched insight into cardiac disease and dysfunction

Oct. 13, 2020
By Annette Boyle
Two teams of researchers have developed miniature models of the human heart that beat and function like the full-size organ.
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