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BioWorld - Sunday, July 3, 2022
Home » Topics » Deals and M&A

Deals and M&A
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Alexion and Stealth cut elamipretide deal

Oct. 11, 2019
By Lee Landenberger
No Comments
Alexion Pharmaceuticals Inc. and Stealth Biotherapeutics Corp. reached a deal for an option to co-develop and commercialize elamipretide for mitochondrial diseases.
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Reata buys top candidate rights back from Abbvie for $330M

Oct. 11, 2019
By Michael Fitzhugh
No Comments
Reata Pharmaceuticals Inc. has agreed to pay former partner Abbvie Inc. $330 million plus royalties to reacquire ex-U.S. development, manufacturing and commercialization rights for the Nrf2 activators bardoxolone methyl and omaveloxolone, as well as other next-generation candidates in the class. Rights to certain Asian markets for bardoxolone remain licensed to Kyowa Kirin Co. Ltd.
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Enabler of inebilizumab: Mitsubishi pact for Viela gets firm $30M up front

Oct. 10, 2019
By Randy Osborne
No Comments
Days after going public, Viela Bio Inc. nailed down a deal with Mitsubishi Tanabe Pharma Corp. to develop and commercialize Viela's humanized anti-CD19 monoclonal antibody, inebilizumab, in nine Asia regions for the rare disease called neuromyelitis optica spectrum disorder (NMOSD), as well as other potential future indications.
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Bluebird, Novo Nordisk to collaborate on genome editing project, starting with hemophilia

Oct. 10, 2019
By Lee Landenberger
No Comments
Bluebird Bio Inc. and Novo Nordisk A/S plan to develop in vivo genome editing treatments for genetic diseases, including hemophilia, over the next three years.
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South Korea's Chong Kun Dang invests in startup Biorchestra targeting Alzheimer's disease

Oct. 10, 2019
By Jihyun Kim
No Comments
HONG KONG – South Korean pharmaceutical company Chong Kun Dang Holdings recently invested KRW5 billion (US$4.1 million) in Biorchestra Co. Ltd., a Korean startup based in Daejeon that aims to develop Alzheimer's dementia treatment based on microRNA.
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Aslan and Bukwang set up JV to advance AhR antagonists

Oct. 9, 2019
By Cornelia Zou
No Comments
HONG KONG – Singapore's Aslan Pharmaceuticals Ltd. and South Korea's Bukwang Pharmaceutical Co. Ltd. have jointly established a new company dedicated to the development of aryl hydrocarbon receptor (AhR) drug candidates. Named Jaguahr Therapeutics Pte. Ltd. – the unusual spelling a clear reference to "AhR" – it will be based in Singapore and will focus on developing immuno-oncology therapeutics for global markets based on the preclinical AhR antagonists in Aslan's early stage pipeline.
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Stealing fire in GI, subsets effort by Prometheus lures Takeda to $420M IBD pact

Oct. 9, 2019
By Randy Osborne
No Comments
CEO Mark McKenna told BioWorld Asia that San Diego-based Prometheus Biosciences Inc. has "cracked the code" in inflammatory bowel disease (IBD) – progress underscored by the firm's deal with Takeda Pharmaceutical Co. Ltd., of Osaka, Japan, which brings an undisclosed up-front payment and as much as $420 million more if development, regulatory and commercial milestones are reached in three programs.
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South Korea's Bioleaders and Israel's Weizmann found JV to advance p53-targeted R&D

Oct. 9, 2019
By Jihyun Kim
No Comments
HONG KONG – South Korean biotech Bioleaders Co. Ltd., headquartered in Yong-in city, Gyeonggi-do, and Israel's Weizmann Institute of Science, based in Rehovot, recently founded a joint venture in Israel. With the new entity, they will accelerate the R&D of a Weizmann-developed approach targeting p53, a strong tumor suppressor that has proved difficult to drug.
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Akcea and Pfizer sign $250M up-front deal

Oct. 8, 2019
By Lee Landenberger
No Comments
Akcea Therapeutics Inc., a majority owned affiliate of Ionis Pharmaceuticals Inc., and Pfizer Inc. signed an exclusive, worldwide licensing deal for AKCEA-ANGPTL-3-LRx, which is being developed to treat cardiovascular and metabolic diseases. The deal follows a period during which Akcea's stock (NASDAQ:AKCA) has sagged prior to rising Monday and big changes in the company's C-suite.
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South Korea's Bioleaders and Israel's Weizmann found JV to advance p53-targeted R&D

Oct. 7, 2019
By Jihyun Kim
No Comments
HONG KONG – South Korean biotech Bioleaders Co. Ltd., headquartered in Yong-in city, Gyeonggi-do, and Israel's Weizmann Institute of Science, based in Rehovot, recently founded a joint venture in Israel. With the new entity, they will accelerate the R&D of a Weizmann-developed approach targeting p53, a strong tumor suppressor that has proved difficult to drug.
Read More
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