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BioWorld - Sunday, July 5, 2026
Home » Topics » Disease categories and therapies » Cancer

Cancer
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Gold chain link engraved with "partnership"

Nurix signs 4th and largest partnership to develop BTK degrader

June 8, 2026
By Brian Orelli
No Comments
Building on its partnerships with Gilead Sciences Inc., Sanofi SA and Pfizer Inc., Nurix Therapeutics Inc. brought on Roche Holding AG to help develop bexobrutideg, an oral degrader of Bruton’s tyrosine kinase (BTK). “I really can’t think of a better partner to maximize the opportunity for bexobrutideg to a wide range of patients,” Jason Kantor, Nurix’s chief business officer, told investors on a conference call, later pointing out that Roche has multiple drugs targeting B cells.
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Cancer

Empire Discovery Institute, Univ. of Rochester identify IRAK inhibitors

June 8, 2026
Empire Discovery Institute and the University of Rochester have discovered new interleukin-1 receptor-associated kinase 1 (IRAK-1) and/or IRAK-4 inhibitors potentially useful for the treatment of cancer, pain, fibrosis and inflammatory disorders.
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Cancer

Antares Therapeutics divulges new CDK2/cyclin E1 inhibitors

June 8, 2026
Antares Therapeutics Inc. has reported new CDK2/cyclin E1 inhibitors potentially useful for the treatment of cancer.
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Cancer

Eikon Therapeutics discloses new USP1 inhibitors

June 8, 2026
Eikon Therapeutics Inc. has disclosed new ubiquitin carboxyl-terminal hydrolase 1 (USP1) inhibitors potentially useful for the treatment of cancer.
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Cancer

Onkure Therapeutics patents new PI3Kα mutant inhibitors

June 8, 2026
Onkure Therapeutics Inc. has disclosed new benzopyridinones acting as phosphatidylinositol 3-kinase α (PI3Kα) mutant inhibitors potentially useful for the treatment of cancer, congenital lipomatous overgrowth, vascular malformations, epidermal naevi and skeletal abnormalities, scoliosis and PIK3CA-related overgrowth spectrum (PROS).
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Art concept for tumor
Cancer

China’s NMPA clears Hansoh’s HS-10541 for clinic

June 8, 2026
No Comments
Hansoh Pharmaceutical Group Co. Ltd. has obtained clinical trial approval from China’s National Medical Products Administration (NMPA) for HS-10541 tablets.
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3D illustration of acute myeloid leukemia cells
Cancer

Amphista’s BRD9 degrader gains IND clearance for AML

June 8, 2026
No Comments
Amphista Therapeutics Ltd. has obtained IND clearance from the FDA for AMX-883, an orally bioavailable degrader of BRD9, for the treatment of acute myeloid leukemia (AML). A phase I trial in patients with relapsed or refractory AML and high-risk myelodysplastic syndrome is expected to begin in the second half of this year.
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China compass

ASCO 2026: Chinese biopharma arrives at ASCO with pivotal wins

June 5, 2026
By Tamra Sami
No Comments
If the 2026 American Society of Clinical Oncology (ASCO) annual meeting in Chicago from May 30 to June 3 demonstrated anything about the evolution of China’s biotechnology sector, it was that the industry’s center of gravity is shifting. While Chinese companies once relied heavily on PD-1 antibodies and licensing deals to gain international visibility, this year’s oral presentations showcased a broader innovation base.
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Deal handshake with coin, chart background

‘Disciplined’ $665M deal moves Oscotec’s cevidoplenib to Agios

June 5, 2026
By Marian (YoonJee) Chu
No Comments
Agios Pharmaceuticals Inc.’s potential $665 million deal for Oscotec Inc.’s cevidoplenib, a phase III-ready oral SYK inhibitor to treat immune thrombocytopenia, marks a new chapter of development focused on cancer therapy resistance for Oscotec, CEO Yoon Tae-young said.
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Cancer

Simcere Zaiming Pharmaceutical discovers new MAPK inhibitors

June 5, 2026
Simcere Zaiming Pharmaceutical Co. Ltd. has divulged new mitogen-activated protein kinase (MAPK) inhibitors found to be potentially useful for the treatment of cancer.
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