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BioWorld - Saturday, July 5, 2025
Home » Topics » Inflammatory, BioWorld

Inflammatory, BioWorld
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Kidneys

Dimerix strikes $601M Amicus deal for kidney disease drug DMX-200

May 1, 2025
By Tamra Sami
Dimerix Ltd. sealed an exclusive license agreement with Amicus Therapeutics Inc. for commercialization of its phase III kidney disease candidate, DMX-200, in a deal valued at AU$940 million (US$601.22 million).
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Approved stamp

South Korea approves record number of biosimilars in 2024

April 30, 2025
By Marian (YoonJee) Chu
South Korea’s Ministry of Food and Drug Safety approved 18 biosimilar products in 2024, making it a record year for domestic biosimilar approvals since the agency’s first nod of Celltrion Inc.’s Remsima, a reference product of Remicade (infliximab), in 2012.
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Blue dollar sign on white background
Newco news

Granite Bio emerges with $100M raised and two immunology assets

April 24, 2025
By Karen Carey
Named after Swiss mountains, Granite Bio AG emerged from stealth with $70 million in funds through a series B to advance two immunology treatments incubated at Versant Ventures.
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Hand holding elbow

Akeso scores China approval for ebdarokimab in plaque psoriasis

April 22, 2025
By Tamra Sami
China’s National Medical Products Administration has given the thumbs up to Akeso Pharmaceuticals Inc.’s ebdarokimab for treating moderate to severe plaque psoriasis in adults. An interleukin (IL)-12/IL-23 dual-targeted monoclonal antibody, ebdarokimab (also known as AK-101) is the company's first class 1 new drug approved for autoimmune diseases.
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Woman scratching hives on shoulder

Dupixent bounces back in treating hives with FDA approval

April 21, 2025
By Lee Landenberger
The U.S. FDA issued a complete response letter in October 2023 for Dupixent (dupilumab) in treating chronic hives but has now approved the monoclonal antibody for the indication. The approval makes Dupixent the first targeted biologic the agency has approved in the past 11 years for chronic spontaneous urticaria.
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Antibodies binding to spike proteins on the surface of SARS-CoV-2 virus
Inflammatory

Australian researchers discover new compound to treat long COVID

April 14, 2025
By Tamra Sami
Researchers have developed a new compound that can prevent long COVID symptoms in mice that could lead to a future drug for the debilitating condition in humans. Developed by researchers at the Walter and Eliza Hall Institute of Medical Research (WEHI) in Melbourne, the world-first study found mice treated with the antiviral compound were protected from long-term brain and lung dysfunction, which are key symptoms of long COVID.
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Newco news

Hillstar launches with $67M series A to target TRBV9+ T cells

March 25, 2025
By Brian Orelli
Hillstar Bio came out of stealth mode, announcing a $67 million series A financing round with investors including Droia Ventures, Frazier Life Sciences, Novo Holdings A/S and Lifearc Ventures.
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US FDA deals second blow to Hengrui-HLB’s liver cancer drug combo

March 21, 2025
By Marian (YoonJee) Chu
The U.S. FDA rejected, for the second time, Elevar Therapeutics Inc.’s NDA of a novel combination therapy for advanced liver cancer, which comprised Jiangsu Hengrui Pharmaceutical Co. Ltd.’s PD-1 inhibitor camrelizumab and HLB Co. Ltd.’s small-molecule tyrosine kinase inhibitor, rivoceranib.
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Insilico Medicine CEO Alex Zhavoronkov with Insilico’s first bipedal humanoid AI Scientist called “Supervisor.”

Insilico advancing AI platform with $110M Asian-backed series E round

March 17, 2025
By Tamra Sami
Artificial intelligence (AI) drug developer Insilico Medicine raised $110 million in a series E round led by an Asian private equity fund, Value Partners Group, that will see Insilico advance its pipeline and AI platform developments.
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Street less than JAK’d about Incyte phase III data in HS

March 17, 2025
By Randy Osborne
Investors wanted more from Incyte Corp.’s top-line results in hidradenitis suppurativa (HS) from its pivotal phase III Stop-HS trial program with oral small-molecule JAK1 inhibitor povorcitinib in adults with moderate to severe disease. Shares of the Wilmington, Del.-based firm (NASDAQ:INCY) closed March 17 at $62.01, down $5.85, after the company made public that Stop-HS1 and Stop-HS2 met the primary endpoint at both tested doses (45 mg and 75 mg)
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