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BioWorld - Wednesday, December 10, 2025
Home » Topics » Disease categories and therapies » Oncology

Oncology
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Businessman and IPO virtual screen

Heartflow prices IPO, Shoulder Innovation joins NYSE

Aug. 1, 2025
By Annette Boyle
Like waves crashing on the beach, med-tech IPOs keep on coming. Heartflow Inc. set terms for its IPO on Aug. 1, offering 12.5 million shares at a price range of $15 to $17 per share. At the top of the range, the company could raise a sunny $212.5 million. It plans to list on the Nasdaq with the symbol “HTFL.”
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Cardiff has positive cancer data but a stock slide, too

July 30, 2025
By Lee Landenberger
No Comments
Cardiff Oncology Inc.’s mid-stage and ongoing clinical trial of its PLK1 inhibitor in colorectal cancer produced promising data but the company’s stock lost a quarter of its value on July 30 because of second-quarter losses. The randomized phase II study of onvansertib combined with a standard-of-care treatment in first-line, RAS-mutated metastatic colorectal cancer produced a 49% confirmed objective response rate at the 30-mg dose level compared to 30% in the control arm.
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Cooler Heads

Cooler Heads chilling with $11M series A

July 22, 2025
By Annette Boyle
Cooler Heads Care Inc. closed an oversubscribed series A, raising a cool $11 million for Amma, its portable scalp cooling system that reduces hair loss during chemotherapy. The new funds will facilitate expanded access to Amma, which is available to patients through infusion centers.
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Plexaa Bloom43

Plexāā Bloom43 to transform breast reconstruction surgery

July 22, 2025
By Shani Alexander
Plexāā Ltd. recently raised $4.5 million to support the upcoming U.S. launch of Bloom43, its wearable device that helps patients prepare for breast cancer surgery and reconstruction by using a technique called supraphysiological preconditioning.
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Sino to acquire Lanova and pipeline for up to $950M

July 22, 2025
By Marian (YoonJee) Chu
No Comments
Sino Biopharmaceutical Ltd. agreed to fully acquire Lanova Medicines Ltd. by buying an additional 95.09% stake in Lanova at a valuation of up to $950.92 million. Considering Lanova’s estimated cash and deposit of $450 million, Hong Kong-headquartered Sino agreed to pay $500.9 million to Lanova on the date of the transaction, set to close within 30 days of all conditions being satisfied, or July 31, 2025.
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Sino to acquire Lanova and pipeline for up to $950M

July 16, 2025
By Marian (YoonJee) Chu
No Comments
Sino Biopharmaceutical Ltd. agreed to fully acquire Lanova Medicines Ltd. by buying an additional 95.09% stake in Lanova at a valuation of up to $950.92 million. Considering Lanova’s estimated cash and deposit of $450 million, Hong Kong-headquartered Sino agreed to pay $500.9 million to Lanova on the date of the transaction, set to close within 30 days of all conditions being satisfied, or July 31, 2025.
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Merger-arrows-black-white.png

BD’s biosciences & diagnostics unit in $17.5B merger with Waters

July 14, 2025
By Annette Boyle
Three months earlier than an expected update on a deal, Becton, Dickinson and Co. reported its biosciences and diagnostic solutions business will combine with Waters Corp. in a transaction valued at $17.5 billion. The resulting enterprise will operate under the Waters name and use its trading symbol (NYSE:WAT). Waters CEO Udit Batra will head the combined company.
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Gears with regulatory words

OIG won’t oppose drugmaker payment for companion diagnostic

July 11, 2025
By Mark McCarty
Companies in the life sciences must tread carefully when it comes to the Anti-Kickback Statute, but a recent advisory opinion by the Office of Inspector General lends little clarity on the point.
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Cancer

Actithera raises $75M series A for FAP-targeted radiopharmaceuticals

July 11, 2025
By Nuala Moran
No Comments
Actithera A/S is poised to bring small-molecule pharmacokinetics to radiopharmaceuticals after closing a $75.5 million series A that will fund initial clinical development of a candidate targeting the elusive fibroblast activation protein (FAP).
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PTAB hands Exact a loss in Geneoscopy patent dispute

July 10, 2025
By Mark McCarty
The med tech patent wars opened a new front in the region of screening tests for colorectal cancer, pitting Exact Sciences Corp., of Madison, Wisc., against St. Louis-based Geneoscopy Inc.
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