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BioWorld - Sunday, December 21, 2025
Home » Topics » Disease categories and therapies » Respiratory

Respiratory
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Lungs wireframe illustration

Owlstone closes $58M series D funding round, readies for IPO

Sep. 7, 2021
By Nuala Moran
LONDON – Breath biopsy specialist Owlstone Medical Ltd. closed a $58 million oversubscribed series D, bringing the total raised by the company since its formation in 2016 to over $150 million. The money will support further development of tests for lung cancer, liver disease and respiratory disease, and of a new class of diagnostics, which rather than measuring endogenous markers of disease, involve administering chemical probes and assessing how they are metabolized.
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AI-driven discovery of novel candidates for idiopathic pulmonary fibrosis

Sep. 7, 2021

BI-1265162, an inhaled ENaC inhibitor for the mutation-agnostic treatment of cystic fibrosis

Sep. 6, 2021

HEC-866, a novel pirfenidone analogue with improved therapeutic efficacy in models of IPF

Sep. 6, 2021

Polyphor setbacks create opportunity for Enbiotix combination

Sep. 2, 2021
By Michael Fitzhugh
Swiss biotech Polyphor AG, left hindered by failures in advanced clinical programs it had pursued in breast cancer and bacterial pneumonia, has found a path forward in a planned merger with Enbiotix Inc. The combination would put Enbiotix Chairman and CEO Jeff Wager in charge of a publicly listed company advancing a combined portfolio of programs for rare disease and cancer, including Polyphor’s inhaled antibiotic, murepavadin, for infections in people with cystic fibrosis.
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Galectin-3 inhibition by tetrahydropyran-based thiodisaccharide mimics

Sep. 2, 2021
Lungs

Study may lead to new pulmonary fibrosis treatments

Aug. 30, 2021
By John Fox
A study led by researchers at Tsinghua University in Beijing has elicited the mechanism whereby the protein leucine-rich repeat kinase 2 prevents alveolar type II epithelial cell dysfunction, limiting profibrotic responses during progression of pulmonary fibrosis.
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Study may lead to new pulmonary fibrosis treatments

Aug. 30, 2021

Blade receives IND clearance for phase I study of cudetaxestat for IPF

Aug. 26, 2021

JadiCells show promise in animal model of COPD

Aug. 24, 2021
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