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BioWorld - Monday, December 8, 2025
Home » Topics » Disease categories and therapies » Respiratory

Respiratory
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Illustration of DNA strand next to lungs
Respiratory

Montse Rosa’s MRT-2359 shows promise in cystic fibrosis

Nov. 6, 2025
No Comments
Montse Rosa Therapeutics Inc. has developed a molecular glue degrader named MRT-2359 that selectively degrades the translation termination factor ERF3A.
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Lungs and bronchi
Respiratory

CGT-001 restores airways CFTR expression

Nov. 5, 2025
No Comments
Carbon Biosciences Inc. has presented data on a parvovirus-based vector that restores full-length cystic fibrosis transmembrane conductance regulator (CFTR) gene for treating cystic fibrosis.
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Handshake with charts, maps, data

Qyuns and Roche partner in $1B+ bispecific antibody deal

Nov. 4, 2025
By Marian (YoonJee) Chu
No Comments
Qyuns Therapeutics Co. Ltd. signed a potential $1.07 billion license deal with Roche Holding AG, granting the latter exclusive rights to QX-031N – a human thymic stromal lymphopoietin and interleukin-33)-targeting bispecific antibody.
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Art concept for inflamed human tissue
Inflammatory

Anti-S100A4 antibody has potential in fibrotic inflammatory disease

Nov. 4, 2025
No Comments
Researchers at Calluna Pharma AS, Agiana Pharmaceuticals AS and Roskilde University have developed the first humanized IgG4 antibody that inhibits S100A4, which is a calcium-binding protein that helps drive fibrotic inflammatory diseases.
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Respiratory

Insmed discovers new cathepsin C inhibitors

Nov. 3, 2025
Insmed Inc. has described cathepsin C (dipeptidyl peptidase I; DPP-1) inhibitors reported to be useful for the treatment of cancer, liver injury, osteoarthritis, heart failure, inflammatory bowel disease, rheumatoid arthritis, bronchiectasis and chronic obstructive pulmonary disease, among others.
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Respiratory

Chinese scientists discover new compounds for respiratory disorders

Oct. 30, 2025
Researchers at Guangzhou Laboratory and Guangzhou Medical University have described compounds reported to be useful for the treatment of asthma, bronchitis, chronic obstructive pulmonary disease (COPD) and infectious pneumonia.
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Handshake with charts, maps, data

Qyuns and Roche partner in $1B+ bispecific antibody deal

Oct. 29, 2025
By Marian (YoonJee) Chu
No Comments
Qyuns Therapeutics Co. Ltd. signed a potential $1.07 billion license deal with Roche Holding AG, granting the latter exclusive rights to QX-031N – a human thymic stromal lymphopoietin and interleukin-33)-targeting bispecific antibody.
Read More
Green and red bispecific antibodies
Respiratory

Roche obtains rights to Qyuns Therapeutics’ respiratory disease candidate

Oct. 29, 2025
No Comments
Qyuns Therapeutics Co. Ltd. has entered into a collaboration and license agreement with F. Hoffmann-La Roche Ltd. granting the latter the exclusive global rights to develop, manufacture and commercialize QX-031N.
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Ena Respiratory's INNA-051

Ena Respiratory raises AU$34M series B to fund phase II trial

Oct. 28, 2025
By Tamra Sami
No Comments
Ena Respiratory Pty Ltd. raised an AU$34 million (US$22.4 million) series B round to advance INNA-051, its nasal spray for symptomatic viral respiratory infections, to phase II trials. New investors in the Melbourne-headquartered company include the Gates Foundation and Flu Lab. Existing investors Brandon Capital, Uniseed and Stoic Venture Capital also participated in the round.
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Memed - Key - Cartridge

NHS trials Memed’s 15-minute blood test in children

Oct. 27, 2025
By Shani Alexander
Trials are being conducted at three pediatric emergency departments in England of the Memed BV rapid blood test, designed to help health care providers distinguish between bacterial and viral infections. The test developed by Memed Diagnostics Ltd. can deliver results in as little as 15 minutes, speeding up the diagnosis of serious conditions such as sepsis or meningitis in children.
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