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Home » Topics » Drugs » Antibody

Antibody
Antibody RSS Feed RSS

Gloved hands holding a heart
Immune

Research consortium to develop immunosuppressive anti-CD40 antibody for cardiac xenotransplantation

Sep. 30, 2022
A research consortium comprised of XL-protein GmbH, Wacker Chemie AG and Ludwig-Maximilians-Universität München (LMU) will develop a novel long-acting immunosuppressive anti-CD40 antibody fragment for the selective suppression of organ rejection, in particular in the area of cardiac xenotransplantation.
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Antibodies
Neurology/Psychiatric

Novel antibody protects from HML-2 Env-mediated neurotoxicity

Sep. 15, 2022
Human endogenous retrovirus-K (HERV-K) belongs to the β-retrovirus-like supergroup of viruses, and it has been previously demonstrated that the expression of HERV-K subtype HML-2 envelope (Env) in human neuronal cultures or in transgenic mice resulted in neurotoxicity and neurodegeneration.
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Immuno-oncology

LB-101, a novel LockBody immunotherapy candidate targeting solid tumors

Sep. 15, 2022
Researchers from Centessa Pharmaceuticals plc presented preclinical data for LB-101, a novel first-in-class immunotherapy targeting solid tumors.
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Antibodies block virus from cell
Infection

SP1-77, a novel broad and potent antibody neutralizing all SARS-CoV-2 variants

Sep. 13, 2022
Researchers from Boston Children’s Hospital and Harvard Medical School reported the discovery and preclinical evaluation of SP1-77, a novel humanized monoclonal IgG-κ antibody targeting the receptor-binding-domain (RBD) of spike (S) glycoprotein of all SARS-CoV-2 variants.
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3D reconstructions of images of HIV vaccine
HIV/AIDS

Experimental HIV vaccine protects macaques against infection

Sep. 13, 2022
By Mar de Miguel
A new vaccine that uses the native-like HIV-1 envelope (Env) trimer CH505 and a Toll-like receptor (TLR) 7/8 agonist adjuvant, successfully evaluated in macaques, generated potent polyclonal neutralizing antibodies (nAbs) and a high protection against the infection of the homologous simian-human immunodeficiency virus (SHIV).
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Breast cancer illustration

Second Probody still bubbling as Cytomx back-burners CX-2009

July 7, 2022
By Randy Osborne

Attention has turned to Cytomx Therapeutics Inc.’s CX-2029 candidate after the company held up its program with the CD166-directed antibody-drug conjugate CX-2009, based on phase II data in patients with hormone receptor-positive/HER2-non-amplified breast cancer.


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Boehringer Ingelheim to develop A*STAR antibodies for targeted cancer therapies

June 14, 2022
By David Ho
Singapore’s Agency for Science, Technology and Research (A*STAR) has inked a deal with Boehringer Ingelheim GmbH to develop and commercialize targeted cancer therapies.
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Boehringer Ingelheim to develop A*STAR antibodies for targeted cancer therapies

June 10, 2022
By David Ho
Singapore’s Agency for Science, Technology and Research (A*STAR) has inked a deal with Boehringer Ingelheim GmbH to develop and commercialize targeted cancer therapies.
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Antibodies attacking cancer cell

Sanofi aims to tweak oncology antibodies, signing $2.5B R&D deal with Adagene

March 8, 2022
By Richard Staines
Adagene Inc. has announced a research collaboration with Sanofi SA, to find “masked” monoclonal and bispecific antibodies that are safer than marketed drugs in oncology, in a deal worth up to $2.5 billion plus royalties. San Diego and Suzhou, China-based Adagene will generate masked versions of Sanofi antibodies, taking responsibility for early stage research activities using its Safebody technology.
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Antibodies attacking cancer cell

Sanofi aims to tweak oncology antibodies, signing $2.5B R&D deal with Adagene

March 2, 2022
By Richard Staines
Adagene Inc. has announced a research collaboration with Sanofi SA, to find “masked” monoclonal and bispecific antibodies that are safer than marketed drugs in oncology, in a deal worth up to $2.5 billion plus royalties. San Diego and Suzhou, China-based Adagene will generate masked versions of Sanofi antibodies, taking responsibility for early stage research activities using its Safebody technology. Sanofi will be responsible for later-stage research and all clinical, product development and marketing activities.
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