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BioWorld - Wednesday, December 10, 2025
Home » Topics » Drugs » Antibody-drug conjugate

Antibody-drug conjugate
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Hand holding dollar sign

Iksuda advancing lead ADC to the clinic with $47M series A financing

June 7, 2021
By Nuala Moran
LONDON – Iksuda Therapeutics Ltd. sealed its transition from technology licensing company to antibody-drug conjugate (ADC) development specialist, closing a $47 million series A financing to move the lead program, IKS-03, into the clinic.
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Antibody

ADC specialist Adcentrx debuts with $50M series A

May 4, 2021
By Elise Mak
Cross-border startup Adcentrx Therapeutics Inc., with operations in San Diego and soon in Shanghai, secured $50 million in a series A financing round led by CBC Group to establish its presence in the antibody-drug conjugate (ADC) space.
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Cancer research illustration
Newco news

Adcendo raises $61M series A round to advance uPARAP-targeting ADC candidate

May 3, 2021
By Nuala Moran
LONDON – In what is claimed as the largest series A for a Danish biotech, Adcendo ApS has raised €51 million (US$61.3 million) to take forward antibody-drug conjugate (ADC) drugs aimed at proprietary targets that are involved in cellular recycling processes.
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Antibody

ADC specialist Adcentrx debuts with $50M series A

April 29, 2021
By Elise Mak
Cross-border startup Adcentrx Therapeutics Inc., with operations in San Diego and soon in Shanghai, secured $50 million in a series A financing round led by CBC Group to establish its presence in the antibody-drug conjugate (ADC) space.
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Peptron Inc. headquarters

Peptron signs global rights for ADC candidate over to Qilu

April 27, 2021
By Elise Mak and Gina Lee
HONG KONG – Qilu Pharmaceutical Ltd. has inked a deal for the global rights to Peptron Inc.’s antibody-drug conjugate (ADC) candidate PAb-001-ADC for the treatment of various cancers. Seoul, South Korea-based Peptron stands to receive an up-front payment of $3 million and $539 million in milestone payments, as well as royalties.
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Peptron Inc. headquarters

Peptron signs global rights for ADC candidate over to Qilu

April 21, 2021
By Gina Lee and Elise Mak
HONG KONG – Qilu Pharmaceutical Ltd. has inked a deal for the global rights to Peptron Inc.’s antibody-drug conjugate (ADC) candidate PAb-001-ADC for the treatment of various cancers. Seoul, South Korea-based Peptron stands to receive an up-front payment of $3 million and $539 million in milestone payments, as well as royalties.
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Pyxis secures $152M series B to advance growing oncology portfolio

March 30, 2021
By Michael Fitzhugh
Pyxis Oncology Inc., a company building a portfolio of antibody-drug conjugates (ADCs) and immunotherapies for cancer, has closed a $152 million series B financing co-led by Arix Bioscience and RTW Investments LP. The fresh funds will help the company advance multiple ADC candidates in-licensed from Pfizer Inc. and Legochem Biosciences Inc. as well as its discovery-stage pipeline, CEO Lara Sullivan told BioWorld. The ADCs are expected to move to the clinic in 2022.
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Target with off-center arrow

Bio-Thera terminates HER2 and Trop2 ADCs and PD-1 inhibitor programs

March 9, 2021
By Elise Mak
In an unusual move for a Chinese company, Bio-Thera Solutions Ltd. terminated the clinical development of its Trop2 antibody-drug conjugate (ADC), BAT-8003, and its PD-1 monoclonal antibody, BAT-1306, a month after it halted the phase III-stage HER2-ADC candidate BAT-8001.
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Antibodies

After phase III failure, Bio-Thera drops batansine technology in favor of new ADC platform

March 8, 2021
Days after taking the unusual step, for a Chinese company, of terminating a couple of clinical programs, Bio-Thera Solutions Ltd. said it still plans to continue R&D in antibody-drug conjugates, but with a new technology platform, the company told BioWorld.
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Target with off-center arrow

Bio-Thera terminates HER2 and Trop2 ADCs and PD-1 inhibitor programs

March 5, 2021
By Elise Mak
In an unusual move for a Chinese company, Bio-Thera Solutions Ltd. terminated the clinical development of its Trop2 antibody-drug conjugate (ADC), BAT-8003, and its PD-1 monoclonal antibody, BAT-1306, a month after it halted the phase III-stage HER2-ADC candidate BAT-8001.
Read More
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