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BioWorld - Saturday, April 11, 2026
Home » Topics » Drugs » Monoclonal antibody

Monoclonal antibody
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Photo of measles rash on skin
Infection

Invivyd unveils measles monoclonal antibody candidate VMS-063

April 10, 2026
No Comments
Invivyd Inc. has announced the discovery and advancement of VMS-063, a novel monoclonal antibody candidate for the treatment and prevention of measles.
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Tape measure, apple on scale
Endocrine/metabolic

Ibio’s IBIO-600 cleared to enter clinic in Australia for obesity

April 9, 2026
No Comments
Ibio Inc. has received clinical trial notification (CTN) acknowledgement from Australia’s Therapeutic Goods Administration (TGA), as well as Human Research Ethics Committee approval, for IBIO-600, enabling the initiation of a first-in-human trial in Australia.
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PET scans showing before and after treatment with VIPOR
ICKSH 2026

Five-drug VIPOR regimen shows promise in aggressive blood cancer

April 7, 2026
By Marian (YoonJee) Chu
No Comments
Deep molecular advances are enabling precision medicine for the field of hematology, Wyndham Wilson said during a plenary session at the 2026 Korean Society of Hematology International Conference March 26.
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Illustration of monoclonal antibody hovering between doctor's hands
Infection

Longhorn reports long-acting peptidoglycan-targeted mAb for sepsis

April 2, 2026
No Comments
At the World Vaccine Congress this week, Longhorn Vaccines & Diagnostics LLC presented the preclinical characterization of LHNVD-501, a half-life-extended, humanized IgG monoclonal antibody (mAb) targeting peptidoglycan (PGN). PGN is a conserved structural component shared across bacterial species and an upstream driver of sepsis, as well as metabolic disease, autoimmune disorders and neurodegeneration.
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PET scans showing before and after treatment with VIPOR
ICKSH 2026

Five-drug VIPOR regimen shows promise in aggressive blood cancer

April 1, 2026
By Marian (YoonJee) Chu
No Comments
Deep molecular advances are enabling precision medicine for the field of hematology, Wyndham Wilson said during a plenary session at the 2026 Korean Society of Hematology International Conference March 26.
Read More
Monoclonal antibody illustration

Simcere’s rademikibart meets phase III endpoints in atopic dermatitis

March 31, 2026
By Tamra Sami
No Comments
Simcere Pharmaceutical Group Ltd.’s monoclonal antibody, rademikibart (CBP-201), met the primary endpoint in a Chinese phase III study in adults and adolescents with moderate to severe atopic dermatitis.
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Immuno-oncology

Tyligand Bioscience divulges new dual-drug antibody-drug conjugates

March 31, 2026
Tyligand Bioscience Ltd. has reported new dual-drug antibody-drug conjugates comprising monoclonal antibodies covalently linked to stimulator of interferon genes protein (STING; TMEM173) agonist and a cytotoxic drug.
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Handshake dollar sign

Novartis buying allergy firm Excellergy for $2B

March 27, 2026
By Karen Carey
No Comments
Just five months after raising a $70 million series A round, newly launched Excellergy Inc. agreed to a $2 billion M&A transaction that would bring its trifunctional allergic effector cell response inhibitors (ECRIs) to Novartis AG.
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Hands holding gears

Gilead pens dual-purpose $2B Ouro M&A deal with Galapagos

March 24, 2026
By Marian (YoonJee) Chu
No Comments
Gilead Sciences Inc. said after U.S. market close March 23 that it will acquire privately held Ouro Medicines LLC and its autoimmune BCMA/CD3 bispecific T-cell engager, gamgertamig, in a deal valued at $2.17 billion.
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Neurology/psychiatric

Acumen reports new Aβ oligomer-targeting antibodies for Alzheimer’s

March 24, 2026
No Comments
Soluble amyloid-β oligomers (AβOs) are known early drivers of Alzheimer’s disease pathogenesis. Acumen Pharmaceuticals Inc. has recently presented data generated in the development and characterization of anti-AβO antibodies with high selectivity for AβO over Aβ monomers.
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