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BioWorld - Thursday, July 3, 2025
Home » Topics » Regions » Europe

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Pill with British pound sign

Pharma execs speak out: UK pricing rebates scare investors

June 4, 2025
By Nuala Moran
No Comments
The row between pharma companies and the U.K. government over rebates has intensified, with the Association of the British Pharmaceutical Industry calling up its members to speak on the record, as it ramps up the campaign against paying back over 23% on sales of branded drugs.
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Amber Implants VCFix Spinal System

Amber Vcfix spinal system shows promising data

June 3, 2025
By Shani Alexander
Amber Implants BV reported no device-related adverse events were seen in any of the patients fitted with its Vcfix spinal system, which treats vertebral compression fractures, at one-year. Data from the first-in-human trial of the device also showed patients experienced a significant reduction in their pain levels.
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Stethoscope, hand, health care icons

NICE says new tech may no longer be required to save on costs

June 3, 2025
By Mark McCarty
The U.K. National Institute for Health and Care Excellence reported it will streamline its health technology assessment, but the bigger news might be that the agency will no longer require new technologies prove to be cost saving to win an endorsement from the agency.
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Amanda Feilding, late co-founder of Beckley Psytech

Atai in $370M merger deal with psychedelic drug specialist Beckley

June 3, 2025
By Nuala Moran
No Comments
Privately held Beckley Psytech Ltd. is to be taken over by Atai Life Sciences in an all-share deal that values the U.K. psychedelic drug specialist at $370 million. After making a $50 million investment in January 2024, Berlin-based Atai already owns 36% of Beckley. It will now issue 105 million new shares to its fellow Beckley investors, giving them 34% ownership of the merged company.
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Boston Scientific Corp overstitch

Rising obesity levels spur endoscopic sleeve uptick

June 2, 2025
By Shani Alexander
While GLP-1 receptor agonists continue to grab the headlines as a treatment option for obesity, another therapy, endoscopic sleeve gastroplasty (ESG), is seeing a steady rise in demand.
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Sanofi-signage on office facade in Edinburgh, U.K.

Sanofi buying Blueprint and its TKI BLU-808 for $9.5B

June 2, 2025
By Nuala Moran
No Comments
Sanofi SA is to acquire Blueprint Medicines Inc. in a $9.5 billion deal that will give the French pharma ownership of a marketed rare disease immunotherapy heading toward blockbuster status, a follow-on product in phase II/III, and a phase II clinical program relevant to a number of autoimmune diseases.
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Green and red bispecific antibodies

Biontech trades half of bispecific BNT-327 to BMS for potential $11B+

June 2, 2025
By Brian Orelli
No Comments
Biontech SE and Bristol Myers Squibb Co. are teaming up to develop Biontech’s BNT-327 in a deal possibly worth over $11 billion. BNT-327 is in the hot new class of bispecific antibodies targeting programmed death-1 (PD-1) or its ligand (PD-L1) and vascular endothelial growth factor (VEGF). The bispecifics take advantage of two well established mechanisms of action that help tumors grow; PD-1/PD-L1, which tells immunogenic T cells not to attack the tumor, and VEGF, which tumors excrete to produce new blood vessels to supply oxygen and other nutrients to the tumor.
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1-30-Abbott-Tendyne.png

Abbott Tendyne TMVR secures FDA clearance

May 30, 2025
By Shani Alexander
Abbott Laboratories recently received FDA clearance for Tendyne, its transcatheter mitral valve replacement system. The news comes on the heels of Edwards Lifesciences Corp. securing a CE mark for its Sapien M3 system and is a boon for mitral valve therapies amid ongoing frustrations about the slow adoption of TMVR technologies.
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EU flag and light bulb

EU launches new strategy supporting growth of innovative startups

May 30, 2025
By Nuala Moran
No Comments
The EU is having another go at improving access to capital for biotechs and science-based startups, in a bid to enable them to remain anchored in Europe. The Startup and Scaleup strategy, announced on May 28, is a response to the long-running problem that although Europe has strong foundations in its academic research, the innovative companies this science spawns often end up being acquired by U.S. companies, or moving to the U.S. to list on Nasdaq or the New York Stock Exchange.
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Microscopic image of a Wilms tumor of a pediatric kidney

More mutations than previously thought in childhood cancers

May 30, 2025
By Nuala Moran
No Comments
Researchers in the U.K. have overthrown the orthodox view that childhood cancers have a low mutation burden, opening up new drug targets and opportunities for repurposing existing therapies. In particular, a high mutation rate is associated with a response to cancer immunotherapy. But although PD-1 checkpoint inhibitors are approved for treating pediatric cancers with a high level of microsatellite instability mutations, in general it is thought childhood tumors are not amenable to immunotherapy.
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