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BioWorld - Sunday, July 20, 2025
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Neurology/psychiatric

Startup Elkedonia raises €11M to advance neuroplastogen in depression

June 13, 2025
By Nuala Moran
No Comments
Newco Elkedonia SAS has raised €11 million (US$12.7 million) in a seed round, which will fund it to take a potentially first-in-class ELK-1 inhibitor into the clinic in the treatment of refractory depression. ELK-1 plays a pivotal role in neuroplasticity and in reward circuits in the brain, which when disrupted can lead to depression, addiction and post-traumatic stress disorder.
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Atalante X Wandercraft

Wandercraft secures $75M in series D funds for robotics portfolio

June 12, 2025
By Shani Alexander
Wandercraft SAS secured $75 million in funding in a series D round to grow its AI-powered robotics solutions. Funds will be spent on its exoskeletons, Atalante X and Eve, as well as on the industrial development and rollout of Calvin 40, its humanoid robot.
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Newco news

Startup Elkedonia raises €11M to advance neuroplastogen in depression

June 12, 2025
By Nuala Moran
No Comments
Newco Elkedonia SAS has raised €11 million (US$12.7 million) in a seed round, which will fund it to take a potentially first-in-class ELK-1 inhibitor into the clinic in the treatment of refractory depression. ELK-1 plays a pivotal role in neuroplasticity and in reward circuits in the brain, which when disrupted can lead to depression, addiction and post-traumatic stress disorder.
Read More
Stock merger illustration

Biontech’s $1.25B Curevac buyout removes mRNA lawsuit uncertainty

June 12, 2025
By Karen Carey
No Comments
Three years after litigation started over technology used in an mRNA vaccine for COVID-19, Biontech SE is acquiring its adversary, Curevac NV, through an all-stock transaction valued at about $1.25 billion. The amount is lower than the $3 billion in backpay Curevac could win through the lawsuit if a low mid-single-digit royalty were awarded, Evercore ISI analysts Jon Miller and Umer Raffat said. But the legal uncertainty has weighed heavily on the company, which shed 30% of its workforce last July and sold off rights to two of its infectious disease vaccines.
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Fineheart Flowmaker

Fineheart pursues FIH study of Flowmaker fully implanted heart pump

June 11, 2025
By Shani Alexander
Fineheart SA will soon begin a first-in-human study of Flowmaker, its fully implantable left ventricular assist device, in France, after receiving authorization from the French National Agency for the Safety of Medicines and Health Products to initiate the trial.
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Money sack with British pound symbol

NHS deploying Histosonics' Edison to slash health care red tape

June 11, 2025
By Mark McCarty
The U.K.’s National Health Service reported June 10 that patients in the U.K. will be the first in Europe to enjoy the benefits of the Edison ultrasound histotripsy for ablation of liver cancer tumors as part of an effort to bring products to market more quickly to deal with unmet needs.
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ABPI: UK’s rebate rates ‘send a terrible message’ to global investors

June 11, 2025
By Nuala Moran
No Comments
The U.K. government has doubled the rate that pharmaceutical companies must repay on sales of branded drugs, under the statutory rebate scheme, to a record 31.3%. Only 1-2% of total sales of branded drugs fall under the statutory scheme, but the increase is seen as a sign that an ongoing review of the voluntary scheme is not going well.
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Philochem, BMS ink $1.35B deal for prostate cancer candidate OncoACp3

June 11, 2025
By Jennifer Boggs
No Comments
Philochem AG’s ligand-targeting approach drew to the table Bristol Myers Squibb Co. in a potential $1.35 billion agreement granting BMS subsidiary Rayzebio Inc. exclusive worldwide rights to OncoACP3, a diagnostic and therapeutic candidate targeting prostate cancer.
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Gold dollar sign

Series B brings Splicebio $135M for Stargardt disease asset

June 11, 2025
By Nuala Moran
No Comments
Three months after dosing the first patient with its dual vector gene therapy, Splicebio SL has closed a $135 million series B to fund the phase I/II trial of SB-007 in the treatment of Stargardt’s disease to completion. Other adeno-associated viru gene therapies for the inherited retinal disorder have entered the clinic, but SB-007 is the first with the capacity to deliver a full version of the ABCA4 gene that underlies Stargardt’s.
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LEX Diagnostics VELO system

Lex seeks FDA clearance ahead of $100M Quidelortho takeover

June 10, 2025
By Shani Alexander
Lex Diagnostics Ltd. has submitted dual applications to the U.S. FDA seeking 510(k) clearance and CLIA waiver status for its Velo system, an ultra-fast point-of-care molecular diagnostics platform. The move comes after the recent news from Quidelortho Corp. that it intends to acquire Lex for $100 million following U.S. regulatory approval of the technology.
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