Origenis GmbH has described cyclin-dependent kinase 9 (CDK9) inhibitors, particularly CDK9/cyclin T1, reported to be useful for the treatment of cancer, viral infections, obesity and more.
A recent bipartisan request for funding of a study on replacing U.S. drug patents with cash prizes is just one more symptom of a larger global malady that makes patents the scapegoat for bigger problems that have nothing to do with intellectual property (IP), David Kappos, board co-chair of the Council for Innovation Promotion (C4IP), told BioWorld.
A recent bipartisan request for funding of a study on replacing U.S. drug patents with cash prizes is just one more symptom of a larger global malady that makes patents the scapegoat for bigger problems that have nothing to do with intellectual property (IP), David Kappos, board co-chair of the Council for Innovation Promotion (C4IP), told BioWorld.
Almac Discovery Ltd. has described heterocyclic compounds acting as ubiquitin C-terminal hydrolase 7 (USP7; HAUSP) inhibitors reported to be useful for the treatment of cancer.
Betta Pharmaceuticals Co. Ltd. has divulged proteolysis targeting chimera (PROTAC) compounds comprising an E3 ubiquitin ligase binding moiety covalently linked to a GTPase KRAS (G12D mutant) targeting moiety via a linker reported to be useful for the treatment of cancer.
Researchers from Antengene Biologics Ltd. and Shanghai Antengene Corp. Ltd. have identified ATR kinase inhibitors reported to be useful for the treatment of cancer.
Jazz Pharmaceuticals plc has synthesized novel amine-substituted phthalazines and derivatives acting as son of sevenless homolog 1 (SOS1)/GTPase KRAS interaction inhibitors reported to be useful for the treatment of cancer.
Shanghai Yidian Pharmaceutical Technology Development Co. Ltd. has disclosed peptidyl nitrile compounds acting as cathepsin C (dipeptidyl peptidase I) inhibitors reported to be useful for the treatment of cancer, infections, diabetes, respiratory, metabolic, cardiovascular, cerebrovascular and autoimmune disease, among others.
“Show us your work” is basically the message the U.S. Court of Appeals for the Federal Circuit sent to the Patent Trial and Appeal Board (PTAB) when it vacated a decision by the board in an ex parte review of rejected patent claims submitted by Theripion Inc. While the Aug. 10 Federal Circuit opinion that remanded the case is nonprecedential, the appellate court made it clear that the PTAB must explain its reasoning for whatever conclusions it reaches.
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