Patents
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Cancer

Biolexis Therapeutics presents new CDK9/cyclin T1 inhibitors

Nov. 6, 2023

Biolexis Therapeutics Inc. has divulged CDK9/cyclin T1 inhibitors reported to be useful for the treatment of cancer, inflammation and autoimmune disease.

Neurology/Psychiatric

Takeda Pharmaceutical describes new OX2 receptor agonists for narcolepsy

Nov. 6, 2023

Takeda Pharmaceutical Co. Ltd. has identified orexin OX2 receptor agonists reported to be useful for the treatment of narcolepsy.

Infection

North Carolina State University divulges new vancomycin derivatives for bacterial infections

Nov. 6, 2023

North Carolina State University has synthesized vancomycin derivatives containing a 2,3-pyrrolidinedione moiety and reported to be useful for the treatment of bacterial infections.

HIV/AIDS

Gilead Sciences patents new compounds for HIV

Nov. 6, 2023

Gilead Sciences Inc. has disclosed bridged tricyclic carbamoylpyridone compounds reported to be useful for the treatment of HIV infection.

Endocrine/Metabolic

Corbus Pharmaceuticals discovers new cannabinoid CB1 receptor antagonists

Nov. 3, 2023

Corbus Pharmaceuticals Holding Inc. has described cannabinoid CB1 receptor antagonists or inverse agonists reported to be useful for the treatment of cancer, dyslipidemia, diabetes, obesity, cardiovascular, inflammatory and liver diseases.

Cancer

Crossignal Therapeutics presents new GPR35 antagonists for cancer

Nov. 3, 2023

Crossignal Therapeutics Inc. has divulged G-protein coupled receptor GPR35 antagonists reported to be useful for the treatment of cancer.

Cancer

Alesta Therapeutics describes new GCN2 inhibitors for cancer

Nov. 3, 2023

Alesta Therapeutics BV has identified eukaryotic translation initiation factor 2-α kinase 4 (GCN2) inhibitors reported to be useful for the treatment of cancer.

Infection

Uniquest divulges new SYK inhibitors

Nov. 3, 2023

Uniquest Pty Ltd. has synthesized tyrosine-protein kinase SYK inhibitors reported to be useful for the treatment of allergy, cancer, fungal infections, rheumatoid arthritis, osteoporosis, liver, lung and periodontal diseases, among others.

Neurology/Psychiatric

Brenig Therapeutics patents new LRRK2 inhibitors for Parkinson’s disease

Nov. 3, 2023

Brenig Therapeutics Inc. has disclosed leucine-rich repeat kinase 2 (LRRK2; dardarin) inhibitors reported to be useful for the treatment of Parkinson’s disease, among others.

Patents

Negev reveals system for improved balance control, stroke rehab

Nov. 2, 2023

By Simon Kerton

Researchers from Israel’s Ben-Gurion University are seeking patent protection for a revamped mechatronic supported in-place walking training system, such as a stepper or elliptical trainer, that provides various types of expected and unexpected perturbations to improve balance control.

Today's news in brief
BioWorld
BioWorld briefs for April 17, 2026.
Biohaven reports details on discovery of BHV-2100
BioWorld Science
Transient receptor potential melastatin 3 (TRPM3) is a calcium-permeable TRP channel that is highly expressed in somatosensory neurons, including nociceptors of...
New GABA(B) receptor PAMs revealed in Addex Pharma patents
BioWorld Science
Addex Pharma SA has disclosed new GABA(B) receptor positive allosteric modulators (PAMs) potentially useful for the treatment of chronic cough, urinary...
Meta-analysis: Anti-amyloid Alzheimer’s drugs not ‘clinically meaningful’
BioWorld
The ongoing controversy over the effectiveness of anti-amyloid drugs is about to get more heated, after a review of clinical trials showed statistically...
Novel caspase-2 inhibitor shows in vivo neuroprotective effects
BioWorld Science
Caspase-2-mediated cleavage of tau at Asp314 generates a neurotoxic fragment, Δtau314, that drives early synaptic dysfunction in Alzheimer’s disease (AD) and...

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