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BioWorld - Wednesday, December 10, 2025
Home » Topics » Infection » Coronavirus

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Immune

Imidazopyrimidine TLR7/8 agonist adjuvant formulation with enhanced Th-polarizing immunity

July 17, 2024
Researchers from Children’s Hospital Boston and affiliated organizations have reported the discovery and preclinical characterization of a novel TLR7/8 agonist adjuvant for vaccination, PVP-037.
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Digital lungs illustration
Respiratory

The TOX-RAGE axis emerges as a potential target for severe pulmonary infections

July 16, 2024
Severe COVID-19 causes a complex lung injury implicating dysregulated immune responses, endothelial dysfunction and coagulopathy, consistent with acute respiratory distress syndrome (ARDS).
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In the clinic for July 9, 2024

July 9, 2024
Clinical updates, including trial initiations, enrollment status and data readouts and publications: AB Science, Cellprothera, Hillevax, Ideaya, Sirnaomics.
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Curevac enters ‘new chapter’ with $1.6B GSK deal, restructuring

July 3, 2024
By Nuala Moran
Curevac AG is casting off the deadweight of its pandemic push to translate its mRNA technology into a marketed COVID-19 vaccine, in a new €1.45 billion (US$1.6 billion) deal in which GSK plc will acquire full rights to infectious disease vaccines the two were co-developing.
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Infection

Pfizer describes new PLpro inhibitors for SARS-CoV-2

July 3, 2024
Pfizer Inc. has identified nonstructural protein 3 (nsp3; PLpro) (SARS-CoV-2; COVID-19 virus) inhibitors reported to be useful for the treatment of SARS-CoV-2 (COVID-19) infection.
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Jaeyong Ahn, CEO and president, SK Bioscience

SK Bioscience to acquire Klocke’s CDMO in cross-holding M&A

July 2, 2024
By Marian (YoonJee) Chu
South Korea’s SK Bioscience Co. Ltd. has entered a cross-shareholding acquisition deal with Germany’s Klocke Pharma-Service GmbH to acquire its contract development and manufacturing organization (CDMO), IDT Biologika Corp.
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Regulatory actions for July 2, 2024

July 2, 2024
Regulatory snapshots, including global drug submissions and approvals, clinical trial approvals and other regulatory decisions and designations: Astrazeneca, Formycon, Humacyte, Idorsia, Longboard, Mesoblast, Sandoz, Springworks, Syncromune, Taurx, Valneva.
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Regulatory actions for July 1, 2024

July 1, 2024
Regulatory snapshots, including global drug submissions and approvals, clinical trial approvals and other regulatory decisions and designations: AB Science, Abbvie, Apellis, ARS, Iovance, Janssen, Merck, Mirum, Moderna, Pfizer, PTC, Regeneron, Rhythm, Roche, Rocket, Shorla, Soleno.
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Jaeyong Ahn, CEO and president, SK Bioscience

SK Bioscience to acquire Klocke’s CDMO in cross-holding M&A

June 27, 2024
By Marian (YoonJee) Chu
South Korea’s SK Bioscience Co. Ltd. has entered a cross-shareholding acquisition deal with Germany’s Klocke Pharma-Service GmbH to acquire its contract development and manufacturing organization (CDMO), IDT Biologika Corp.
Read More

In the clinic for June 26, 2024

June 26, 2024
Clinical updates, including trial initiations, enrollment status and data readouts and publications: Ascendis, Astrazeneca, Bioxcel, Douglas, Ethris, Innovent, Lipocine, Merck KGaA, Novo, Soligenix, Tevogen, Wave Life, Werewolf.
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