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BioWorld - Monday, December 29, 2025
Home » Topics » Infection » Coronavirus

Coronavirus
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Infection

Aligos and KU Leuven synthesize new Mpro inhibitors

May 29, 2024
Aligos Therapeutics Inc. and Katholieke Universiteit Leuven (KU Leuven ) have jointly developed new 3C-like proteinase (3CLpro; Mpro; nsp5) (SARS-CoV-2; COVID-19 virus) inhibitors reported to be useful for the treatment of SARS-CoV-2 infection (COVID-19), rhinovirus and norovirus infections.
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USTR seal

Usual players show up again in US trade report of bad actors

May 21, 2024
By Mari Serebrov
The U.S. Trade Representative (USTR) once again called out the usual cast of characters in this year’s Special 301 Report for not playing by the rules when it comes to protecting intellectual property. And once again, industry asked the USTR to go further by placing new players on the list.
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Report leads to suspension of Ecohealth, NIH rebuke

May 21, 2024
By Mari Serebrov
Citing the need to protect the public interest, the U.S. Department of Health and Human Services ordered an immediate government-wide funding suspension May 15 of Ecohealth Alliance Inc. while formal debarment proceedings are pending against the New York-based nongovernmental organization.
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In the clinic for May 20, 2024

May 20, 2024
Clinical updates, including trial initiations, enrollment status and data readouts and publications: Achieve, Astrazeneca, Bayer, BMS, Hutchmed, Inventiva, Marinus, Recce.
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Report leads to suspension of Ecohealth, NIH rebuke

May 16, 2024
By Mari Serebrov
Citing the need to protect the public interest, the U.S. Department of Health and Human Services ordered an immediate government-wide funding suspension May 15 of Ecohealth Alliance Inc. while formal debarment proceedings are pending against the New York-based nongovernmental organization.
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Oral medication

Shionogi’s COVID-19 drug misses endpoint in global phase III

May 14, 2024
By Marian (YoonJee) Chu
Osaka, Japan-based Shionogi & Co. Ltd. said May 13 that ensitrelvir fumaric acid (Xocova), its oral antiviral for COVID-19, showed no statistical difference against placebo in completely resolving 15 common COVID-19-related symptoms in a global phase III Scorpio-HR trial.
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In the clinic for May 14, 2024

May 14, 2024
Clinical updates, including trial initiations, enrollment status and data readouts and publications: Ascendis, BMS, Bridgebio, Cardurion, Cytokinetics, Delix, Excision, Imunon, Inventiva, Jasper, Merck & Co., Newron, Senti, Valneva.
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Nuvaxovid

Novavax storms back with $1.2B Sanofi deal

May 10, 2024
By Lee Landenberger
A licensing deal worth potentially up to $1.2 billion with Sanofi SA has breathed new life into Novavax Inc., which has struggled to compete in the COVID-19 space with powerhouses Pfizer Inc. and Moderna Inc.
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Infection

Roche divulges new 3CLpro inhibitors

May 9, 2024
Researchers at F. Hoffmann-La Roche Ltd. and Hoffmann-La Roche Inc. have synthesized 3C-like proteinase (3CLpro, Mpro) (coronavirus) inhibitors reported to be useful for the treatment of coronavirus acute respiratory syndrome infections.
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In the clinic for May 8, 2024

May 8, 2024
Clinical updates, including trial initiations, enrollment status and data readouts and publications: Achieve, Calliditas, Eledon, Eyedna, Inmagene, Mirum, Moleculin, Neurogene, Neurosense, Rion, Traws, Verve.
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