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Dermatologic

Haisco Pharmaceutical describes new TNF-α/TNFR1 interaction inhibitors

Oct. 13, 2025
Haisco Pharmaceutical Group Co. Ltd. has identified compounds acting as TNF-α/TNF receptor superfamily member 1A (TNFR1) interaction inhibitors reported to be useful for the treatment of psoriasis and rheumatoid arthritis.
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Infection

CSPC Zhongqi Pharmaceutical Technology divulges new CEN inhibitors

Oct. 13, 2025
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co. Ltd. has synthesized prodrugs of deuterated baloxavir marboxil derivatives acting as cap-dependent endonuclease (CEN) (influenza virus) inhibitors reported to be useful for the treatment of influenza viral infections.
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Cancer

Chia Tai Tianqing Pharmaceutical patents new BCL6 degradation inducers

Oct. 13, 2025
Chia Tai Tianqing Pharmaceutical Group Co. Ltd. has disclosed proteolysis targeting chimeric (PROTAC) compounds comprising cereblon (CRBN) ligands covalently bonded to a B-cell lymphoma 6 protein (BCL6)-targeting moiety through a linker.
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Cancer

Shandong Simcere Medgenn Bio-Pharmaceutical discovers new CDK4/cyclin D1 inhibitors

Oct. 10, 2025
Shandong Simcere Medgenn Bio-Pharmaceutical Co. Ltd. has described CDK4/cyclin D1 inhibitors reported to be useful for the treatment of cancer.
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Neurology/psychiatric

Myrobalan Therapeutics describes new GPR17 antagonists

Oct. 10, 2025
Myrobalan Therapeutics Nanjing Co. Ltd. has divulged uracil nucleotide/cysteinyl leukotriene receptor (GPR17; P2Y-like) antagonists reported to be useful for the treatment of multiple sclerosis, amyotrophic lateral sclerosis, Alzheimer’s disease and Parkinson’s disease.
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Neurology/psychiatric

New compounds for anesthesia disclosed in Kelun Pharmaceutical patent

Oct. 10, 2025
Sichuan Kelun Pharmaceutical Research Institute Co. Ltd. and Suzhou Kelun Pharmaceutical Co. Ltd. have identified carboxylic acid ester compounds reported to be useful for anesthesia.
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Immuno-oncology

Beijing Chempion Biotechnology divulges new FOLR1-targeting ADCs

Oct. 10, 2025
Beijing Chempion Biotechnology Co. Ltd. has synthesized antibody-drug conjugates comprising antibodies targeting folate receptor α (FOLR1; FR-α) covalently linked to a cytotoxic drug through a linker reported to be useful for the treatment of cancer.
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Cancer

Beijing Avistone Pharmaceuticals Biotechnology patents new HER2 inhibitors

Oct. 10, 2025
Beijing Avistone Pharmaceuticals Biotechnology Co. Ltd. has disclosed spiro/bridged ring compounds acting as HER2 (erbB2) (exon 20 insertion [Ex20Ins] [Ala775_Gly776insTyrValMetAla mutant]) inhibitors reported to be useful for the treatment of atherosclerosis, cancer and pulmonary fibrosis.
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Neurology/psychiatric

Casma Therapeutics identifies MCOLN1 activators

Oct. 9, 2025
Casma Therapeutics Inc. has developed bicyclic heteroaromatic compounds acting as mucolipin-1 (MCOLN1; TRPML1) activators reported to be useful for the treatment of Duchenne muscular dystrophy, neurodegeneration, atherosclerosis, cancer, infections, liver, lysosomal storage and inflammatory bowel diseases.
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Diagnostics

Canadian researchers report radiolabeled diagnostic agents

Oct. 9, 2025
Simon Fraser University, TRIUMF and the University of British Columbia have disclosed radiolabeled compounds reported to be useful for the diagnosis of cancer.
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