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BioWorld - Friday, February 13, 2026
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BioWorld Science, Patents
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Neurology/psychiatric

New compounds for anesthesia disclosed in Kelun Pharmaceutical patent

Oct. 10, 2025
Sichuan Kelun Pharmaceutical Research Institute Co. Ltd. and Suzhou Kelun Pharmaceutical Co. Ltd. have identified carboxylic acid ester compounds reported to be useful for anesthesia.
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Immuno-oncology

Beijing Chempion Biotechnology divulges new FOLR1-targeting ADCs

Oct. 10, 2025
Beijing Chempion Biotechnology Co. Ltd. has synthesized antibody-drug conjugates comprising antibodies targeting folate receptor α (FOLR1; FR-α) covalently linked to a cytotoxic drug through a linker reported to be useful for the treatment of cancer.
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Cancer

Beijing Avistone Pharmaceuticals Biotechnology patents new HER2 inhibitors

Oct. 10, 2025
Beijing Avistone Pharmaceuticals Biotechnology Co. Ltd. has disclosed spiro/bridged ring compounds acting as HER2 (erbB2) (exon 20 insertion [Ex20Ins] [Ala775_Gly776insTyrValMetAla mutant]) inhibitors reported to be useful for the treatment of atherosclerosis, cancer and pulmonary fibrosis.
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Neurology/psychiatric

Casma Therapeutics identifies MCOLN1 activators

Oct. 9, 2025
Casma Therapeutics Inc. has developed bicyclic heteroaromatic compounds acting as mucolipin-1 (MCOLN1; TRPML1) activators reported to be useful for the treatment of Duchenne muscular dystrophy, neurodegeneration, atherosclerosis, cancer, infections, liver, lysosomal storage and inflammatory bowel diseases.
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Diagnostics

Canadian researchers report radiolabeled diagnostic agents

Oct. 9, 2025
Simon Fraser University, TRIUMF and the University of British Columbia have disclosed radiolabeled compounds reported to be useful for the diagnosis of cancer.
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Cancer

Convalife Pharmaceuticals divulges KIF18A inhibitors

Oct. 9, 2025
Convalife Pharmaceuticals Co. Ltd. and Zhejiang Convalife Pharmaceutical Co. Ltd. have discovered sulfanilamide compounds acting as kinesin-like protein KIF18A inhibitors reported to be useful for the treatment of cancer, inflammatory disorders and ciliopathy.
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Infection

New DHFR inhibitors disclosed in Shenzhen Bay Laboratory patent

Oct. 9, 2025
Shenzhen Bay Laboratory has synthesized fused ring derivatives acting as dihydrofolate reductase (DHFR) (bacterial) inhibitors reported to be useful for the treatment of cancer, bacterial, fungal, nematode and viral infections.
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Endocrine/metabolic

Pfizer patents SLC6A19 inhibitors

Oct. 9, 2025
Pfizer Inc. has identified new indole analogues acting as sodium-dependent neutral amino acid transporter B(0)AT1 (SLC6A19) inhibitors reported to be useful for the treatment of diabetes, chronic kidney disease, metabolic dysfunction-associated steatotic liver disease (NAFLD; MASLD), phenylketonuria, metabolic syndrome, obesity, neurodevelopmental and autism-spectrum disorders, among others.
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HIV/AIDS

HIV-1 targeted activator of cell kill compounds divulged in MSD patent

Oct. 8, 2025
Merck Sharp & Dohme LLC (MSD) has synthesized new N-oxide derivative targeted activator of cell kill (TACK) compounds acting as Gag polyprotein (HIV-1)/protein Pol dimerization inducers reported to be useful for the treatment of HIV infection.
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Neurology/psychiatric

Northern Illinois University and Stream Neuroscience report PDE4 inhibitors

Oct. 8, 2025
Northern Illinois University and Stream Neuroscience Inc. have patented benzothiazole derivatives acting as phosphodiesterase‑4 (PDE4) inhibitors and reported to be useful for the treatment of cancer, cognitive, inflammatory and mood disorders.
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