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Discovery of GB-1101, selective oral HDAC6 inhibitor with potent antitumor activity in vivo

May 9, 2022

CDK7 inhibitor GTAEXS-617 shows potent antitumor activity in vivo

May 5, 2022

CRD-1600 demonstrates robust immune modulatory properties in vitro and in vivo

May 4, 2022

GTX-0196 shows complete tumor growth suppression in models of AML

May 4, 2022

Bridge Biotherapeutics and Cyrus Therapeutics generate next-generation EGFR degraders

May 2, 2022

BBT-207, a fourth-generation EGFR TKI with activity against most common mutants

May 2, 2022

AC-0027875, a gamma-secretase modulator for the treatment of AD

April 29, 2022

KSHN-001034, a novel prodrug that delivers higher fulvestrant concentrations

April 28, 2022

ARTS-021 shows promising antitumor activity in CCNE1-amplified cancer models

April 27, 2022

ZLD-2218, a novel BRD4 inhibitor for the treatment of kidney fibrosis

April 26, 2022

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Today's news in brief
BioWorld
BioWorld briefs for May 4, 2026.
University of Western Australia patents 5-HT2A/B modulators
BioWorld Science
University of Western Australia has identified new lysergic acid diethylamide (LSD) analogues acting as 5-HT2A and 5-HT2B modulators reported to be useful for the...
Alceptor Therapeutics discovers new α2B-adrenoceptor agonists
BioWorld Science
Alceptor Therapeutics Inc. has patented new pyrazol-5-amine α2B-adrenoceptor agonists reported to be useful for the treatment of pain and hypertension.
EQ-504 is AhR agonist for ulcerative colitis, related disorders
BioWorld Science
Activating the aryl hydrocarbon receptor (AhR) in immune cells enhances anti-inflammatory pathways and limits pathogenic immune responses. Equillium Inc. has...
Quintuple GLP-1–GIP–PPAR agonist for obesity and diabetes control
BioWorld
A new molecule combines the action of two incretins, GLP-1 and GIP, hormones that regulate glucose and appetite, with lanifibranor, a triple agonist of peroxisome...