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Artistic rendering of the KRAS protein.

Aimedbio’s solid tumor ADC asset goes to Boehringer in $1B deal

Oct. 16, 2025
By Marian (YoonJee) Chu
No Comments
Antibody-drug conjugate (ADC) specialist Aimedbio Inc. announced Oct. 16 the signing of a potential $991 million deal with Boehringer Ingelheim GmbH to license out its novel preclinical ADC asset targeting solid tumors, including KRAS mutations, which is set to enter phase I study next year.
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White Euro symbol on blue background

Adcytherix raises $122M series A to develop novel ADCs

Oct. 16, 2025
By Nuala Moran
No Comments
A year and half from its inception, Adcytherix SAS has raised a €105 million (US$122 million) series A, enabling it to take the lead antibody-drug conjugate (ADC) program into clinical development next year.
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Herpes simplex virus

Aicuris to file pritelivir NDA on positive phase III data in herpes infections

Oct. 16, 2025
By Nuala Moran
No Comments
Aicuris Anti-Infective Cures AG is preparing to file for U.S. FDA approval after reporting positive phase III results for lead antiviral pritelivir in the healing of refractory herpes simplex virus lesions in immunocompromised patients.
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Concept of business partnership

Leads Biolabs joins a $1B development deal with Dianthus

Oct. 16, 2025
By Lee Landenberger
No Comments
Dianthus Therapeutics Inc. has joined the recent trend of companies licensing therapies in development from China. The company will pay as much as $1 billion to Nanjing Leads Biolabs Co. Ltd. for DNTH-212, a bifunctional BDCA2 and BAFF/APRIL inhibitor to treat autoimmune disorders.
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Shaky hands holding glass

Praxis soars on essential tremor phase III, preps for NDA

Oct. 16, 2025
By Karen Carey
No Comments
Success by nearly all measures with Praxis Precision Medicines Inc.’s essential tremor phase III candidate, ulixacaltamide, drove the company’s stock up significantly and provided solid data for an NDA filing planned for early 2026.
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3D rendering of 2-Arachidonoylglycerol (2-AG) endocannabinoid neurotransmitter molecule

ECNP 2025: Endocannabinoids have metabolic role in mental health

Oct. 16, 2025
By Anette Breindl
No Comments
At the 2025 European College of Neuropsychopharmacology (ECNP) Congress in Amsterdam this week, researchers presented new findings on the role of endocannabinoids in stress, addiction … and the integrity of the blood-brain-barrier.
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Omeros riding high on $2.1B deal with Novo for PNH drug

Oct. 15, 2025
No Comments
A preview of the next edition of BioWorld, Oct. 15, 2025
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Regulatory actions for Oct. 15, 2025

Oct. 15, 2025
Regulatory snapshots, including global drug submissions and approvals, and other regulatory decisions and designations: Abbvie, Akamis, Blacksmith, Cingulate, Corcept, Denali, GSK, Johnson & Johnson, Legend, Krystal, Rocket.
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Other news to note for Oct. 15, 2025

Oct. 15, 2025
Biopharma happenings, including deals and partnerships, and other news in brief: Boehringer Ingelheim, Cytomed, Frontier, Johnson & Johnson, Nabla, Novo Nordisk, Quantro, Sumitomo, Takeda, TC.
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In the clinic for Oct. 15, 2025

Oct. 15, 2025
Clinical updates, including data readouts and publications: Alzheon, Bioxcel, Candel, Celularity, Clover, Ionctura, Lexicon, Oticara, Pfizer, Remegen, Spyglass, Transcode, UCB, Vor.
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