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BioWorld - Monday, March 2, 2026
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Gilead-Genhouse's $1.5B+ deal boosts synthetic lethality push

Feb. 24, 2026
By Tamra Sami
No Comments
Gilead Sciences is stepping deeper into synthetic lethality, licensing a clinic-ready MAT2A (methionine adenosyltransferase 2a) inhibitor from Suzhou, China-based Genhouse Bio Co. Ltd. in a deal worth up to $1.53 billion.
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Illustration of CTLA-4 protein structure
Newco news

Harbour Biomed spins out newco in $1.2B CTLA-4 deal

Feb. 24, 2026
By Tamra Sami
No Comments
Harbour Biomed is spinning out newco Solstice Oncology and is outlicensing its CTLA-4 antibody, porustobart (HBM-4003), to the newco in a cash and equity deal worth more than $1.2 billion.
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3D dollar sign

Ascletis raises $107M to advance oral GLP-1 to phase III trials

Feb. 24, 2026
By Tamra Sami
No Comments
Ascletis Pharma Inc. raised HK$843.53 million (US107.93 million) in a placement on the Hong Kong Stock Exchange to advance its lead program, ASC-30, a small-molecule glucagon-like peptide-1 (GLP-1) receptor agonist that can be dosed once monthly subcutaneously and once daily orally for treating obesity.
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Takeda’s oral narcolepsy drug steps closer to FDA approval

Feb. 24, 2026
By Marian (YoonJee) Chu
No Comments

The U.S. FDA accepted, with priority review, Takeda Pharmaceutical Co. Ltd.’s NDA submission for oveporexton (TAK-681), bringing the oral orexin receptor 2 agonist closer to clearance in narcolepsy type 1.


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Madrigal adds siRNA approach to MASH pipeline in $4.4B Ribo deal

Feb. 24, 2026
No Comments
Continuing to build on the successful launch of Rezdiffra (resmetirom), Madrigal Pharmaceuticals Inc. is adding six preclinical-stage siRNA therapies to its metabolic dysfunction-associated steatohepatitis (MASH) pipeline in a deal with Ribo Life Science Co. Ltd. and its subsidiary, Ribocure Pharmaceuticals AB, that could be worth $4.4 billion if all milestones are achieved.
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Interleukin 17 (IL-17)
Newco news

Quantx raises $85M to advance oral immunology drugs

Feb. 24, 2026
By Tamra Sami
No Comments
After closing an oversubscribed $85 million series B round, Quantx Biosciences Inc. is gearing up to begin clinical trials of its two lead immunology compounds, a STAT6 oral small-molecule inhibitor and an IL-17 oral small-molecule inhibitor.
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Biopharma approvals January 2026

China tops US in January drug approvals

Feb. 24, 2026
By Amanda Lanier
No Comments
U.S. FDA approvals began 2026 at a slower pace than usual, with eight approvals recorded in January.
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China compass

Innovent-Lilly $8.5B deal signals new China inflection point

Feb. 10, 2026
By Tamra Sami
No Comments
The scale of the $8.5 billion deal signed between Innovent Biologics Inc. and Eli Lilly and Co. is eye-catching, but the structure is the real signal. By shifting phase II oncology development to China while reserving global rights ex-greater China, the partners are testing a model that could reshape how multinational drugmakers source innovation as well as how Chinese biotechs create value.
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Gavel and block with Chinese flag

China amends drug rules to enforce lifecycle accountability

Feb. 10, 2026
By Tamra Sami
No Comments
China’s State Council updated its Drug Administration Law, and the changes mark a substantive evolution in the country’s drug regulatory framework.
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Insight Lifetech IPO ceremony

Heart intervention device-maker Insight lands $143M SSE IPO

Feb. 10, 2026
By Marian (YoonJee) Chu
No Comments
Insight Lifetech Co. Ltd. listed on the Shanghai Stock Exchange’s STAR market via an unprofitable biotech track reinstated last year, with the Feb. 5 IPO raising ¥998.64 million (US$143.93 million).
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