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BioWorld - Friday, December 19, 2025
Home » Authors » Anette Breindl

Articles by Anette Breindl

Immunotherapy Moving from Hype Cycle into Remissions

June 6, 2012
By Anette Breindl
CHICAGO – On the last day of the 2012 American Society of Clinical Oncology (ASCO) meeting, the crowds had thinned enough so that the convention center staff no longer had an individual on duty in the East Hall whose sole task it was to exhort conventioneers to "stay right by order of the fire marshal."
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@ASCO12: Invisible Gorillas, IgNobel Prizes and What it All Means for Drug Discovery

June 5, 2012
By Anette Breindl
As I may have mentioned before, I love the IgNobel Prizes. So imagine my delight when I found myself in a session at ASCO’s 2012 annual meeting earlier this week listening to the speaker, Anthony Tolcher, talking about The Invisible Gorilla. (If you haven’t heard about the experiment that demonstrated the existence of invisible gorillas, you can try it for yourself with this video. But do it before you read the rest of this blog post, because it will not work if you know what it’s about.) In short, the invisible gorilla is a jarring example of what Christopher Chabris...
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Finally, Progress Reported in Treatment of Lung Cancer

June 5, 2012
By Anette Breindl
CHICAGO – With five-year survival rates of 15 percent, lung cancer treatment is not, overall, one of oncology's poster children. Partly, that's due to the sheer genomic complexity of the disease. And the disease, like its most frequent cause, smoking, comes with social stigma.
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T-DM1 Slows Breast Cancer, with Fewer Side Effects

June 5, 2012
By Anette Breindl
CHICAGO – Roche AG subsidiary Genentech Inc. and partner ImmunoGen Inc. had what looks to be another winner at Sunday's plenary session of the American Society of Clinical Oncology (ASCO) annual meeting.
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Lung, Other Tumors Respond to PD1-Targeting Immunotherapy

June 4, 2012
By Anette Breindl
CHICAGO – Given the fact that President Obama was in Chicago for his own purposes on Friday and Saturday, leading to posted warnings about possible travel delays in the conference shuttles, the first astounding bit of news out of the American Society of Clinical Oncology (ASCO) meeting may have been that all speakers made it to the opening press briefing.
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Designer Proteins Self-Assemble into Complex, Exact Structures

June 1, 2012
By Anette Breindl
Two groups reported new advances this week in one area of bio-nanotechnology, namely the quest to design protein units that can self-assemble into more complex structures.
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Alternative to Surface Markers Can Be Used to Sort Stem Cells

May 30, 2012
By Anette Breindl
Scientists have identified a new characteristic that could be used to identify progenitor cells that are particularly likely to differentiate into bone, cartilage and fat, respectively. Instead of the usual cell surface markers, they measured the mechanical characteristics of one type of stem cell, the mesenchymal stem cell, and were able to predict whether a given cell was more likely to differentiate into bone, cartilage or fat.
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Drugs Lead to Autoimmunity via Effects on HLA Binding

May 29, 2012
By Anette Breindl
Two studies reported new insights into the origins of drug hypersensitivity.
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To Drug the Undruggables, First Think the Unthinkable

May 29, 2012
By Anette Breindl
The statistic showing that more than one-third of currently marketed drugs target G-protein coupled receptors is often quoted as evidence that those receptors make good drug targets. And they do. But such convergence is also evidence that although drug discovery is a vast endeavor, in some ways it could be described as a mile wide and an inch deep.
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Adenosine Treatment Could Cement Success of Implants

May 24, 2012
By Anette Breindl
Researchers at the New York University School of Medicine have identified a treatment that they hope will extend the life expectancy of implants. In animal experiments, treatment with agonists of the adenosine 2A receptor prevented the inflammation and subsequent bone loss that is one of the leading causes of prosthesis loosening and implant failure.
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