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BioWorld - Friday, December 26, 2025
Home » Authors » Brian Orelli

Articles by Brian Orelli

Immuno-oncology boosting R&D, spurring collaborations

March 14, 2016
By Brian Orelli
The promise of immuno-oncology has attracted many players to the space. More than 130 biotechs and 20 pharmaceutical companies are working on immuno-oncology therapies, according to a new report from the Tufts Center for the Study of Drug Development.
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Firms look to new MOAs to treat Alzheimer’s disease

March 7, 2016
By Brian Orelli
As Biogen Inc., Merck & Co. Inc. and Eli Lilly and Co. race to the finish line with their Alzheimer’s disease drugs that are in phase III development, two companies – Neuro-Bio Ltd. and Ironwood Pharmaceuticals Inc. – are just lacing up their shoes.
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Panel: Cranking out biopharma newcos with a build-to-sell model

Feb. 29, 2016
By Brian Orelli
SAN DIEGO – At the Biocom Global Life Science Partnering Conference, biotech executives and venture capitalists shared their experiences building companies with the intention of selling to a big pharma.
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Investors upbeat on biopharma but warn 2016 may be rough

Feb. 29, 2016
By Brian Orelli
SAN DIEGO – The mood at the Biocom Global Life Science Partnering Conference last week was generally upbeat on the long-term future of the sector, but venture capitalists, investment bankers, serial entrepreneurs, and other speakers at the conference warned that 2016 might be rough for raising capital.
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Precision medicine pushes bioinformatics to the cloud

Feb. 22, 2016
By Brian Orelli
Like seemingly everything having to do with computers these days, bioinformatics is pushing into the cloud, allowing for cheaper and more efficient computation to identify potential targets for precision medicine.
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Fighting resistance with novel mechanisms of action

Feb. 8, 2016
By Brian Orelli
With the rising increase in bacteria and fungus resistant to current medications, companies are developing drugs that use novel mechanisms of action to fight the bugs.
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Pricing and integration keys for biotech moving forward

Feb. 1, 2016
By Brian Orelli
While the biotech industry has come a long way in developing new innovative drugs, companies will face external and internal issues in 2016, according to a new report from the Tufts Center for the Study of Drug Development (CSDD).
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Injecting patient compliance into HIV drug regimens

Jan. 25, 2016
By Brian Orelli
Highly active antiretroviral therapies (HAART), combining multiple drugs into a cocktail, can effectively suppress HIV. But patient compliance in taking pills, especially after the virus becomes resistant and requires multiple pills per day, can be a challenge.
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Big VC financing rounds lead to monster 4Q

Jan. 5, 2016
By Brian Orelli
Venture capitalists hit the ground running after returning from their summer vacations that saw third-quarter investments fall substantially from the first half. (See BioWorld Today, Oct. 2, 2015.)
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If you can't beat 'em join 'em; looking for immuno-onc boost

Dec. 14, 2015
By Brian Orelli
Last week, Threshold Pharmaceuticals Inc. announced the failure of two phase III evofosfamide trials, one in pancreatic cancer and another in soft tissue sarcoma, but Barry Selick, CEO of the South San Francisco-based company, gave investors some hope that the drug might work in combination with immune checkpoint inhibitors.
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