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BioWorld - Sunday, April 26, 2026
Home » Authors » Brian Orelli

Brian Orelli

Articles

ARTICLES

Roche 'Ignyta' fire in M&A targeted therapy takeout

Dec. 27, 2017
By Brian Orelli
Roche Holding AG is acquiring San Diego-based Ignyta Inc. for $1.7 billion with an offer of $27 per share in cash, a 74 percent increase over its closing price on Thursday.
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Aerie gets present from the FDA in Rhopressa early nod

Dec. 20, 2017
By Brian Orelli
Christmas came early for Aerie Pharmaceuticals Inc. with an FDA approval of Rhopressa (netarsudil) for open-angle glaucoma or ocular hypertension on Monday – or maybe call it an early Valentine's Day gift considering the PDUFA goal date wasn't until Feb. 28, 2018.
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Companies seek HIV holy grails: A vaccine or a cure

Dec. 11, 2017
By Brian Orelli
Many companies have tried and failed to make an HIV vaccine capable of preventing HIV infection, but the virus has eluded more than 30 vaccines so far.
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Companies seek HIV holy grails: A vaccine or a cure

Dec. 11, 2017
By Brian Orelli
Many companies have tried and failed to make an HIV vaccine capable of preventing HIV infection, but the virus has eluded more than 30 vaccines so far.
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Winners and losers from the FDA approval class of 2014

Nov. 27, 2017
By Brian Orelli
Immuno-oncology drugs Keytruda (pembrolizumab, Merck & Co. Inc.) and Opdivo (nivolumab, Bristol-Myers Squibb Co.) came in first and third in the latest edition of the Trinity Drug Index, with hepatitis C drug Harvoni (sofosbuvir/ledipasvir, Gilead Sciences Inc.) taking the second spot. This version of the annual index scores the 41 drugs approved by the FDA in 2014 based on commercial, therapeutic and R&D categories.
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Winners and losers from the FDA approval class of 2014

Nov. 27, 2017
By Brian Orelli
Immuno-oncology drugs Keytruda (pembrolizumab, Merck & Co. Inc.) and Opdivo (nivolumab, Bristol-Myers Squibb Co.) came in first and third in the latest edition of the Trinity Drug Index, with hepatitis C drug Harvoni (sofosbuvir/ledipasvir, Gilead Sciences Inc.) taking the second spot. This version of the annual index scores the 41 drugs approved by the FDA in 2014 based on commercial, therapeutic and R&D categories.
Read More

Single-source manufacturing faster, cheaper in long run

Nov. 13, 2017
By Brian Orelli
The old saying "many hands make quick work" doesn't apply to drug manufacturing for use in clinical trials, according to a new study from The Tufts Center for the Study of Drug Development (CSDD) looking at single-source vs. multivendor manufacturing at contract development and manufacturing organizations (CDMOs).
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Oncology drugs move to China seeking patients and approvals

Oct. 30, 2017
By Brian Orelli
With a third of the world's cancer patients residing in China and upward of half of them enrolling in clinical trials, small U.S.-based companies are looking across the Pacific to test their oncology drug candidates.
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AI drug development lands endorsements from pharma, VC

Oct. 20, 2017
By Brian Orelli
The use of artificial intelligence (AI) in drug development has increased substantially over the last few years. And both large pharmaceutical companies and venture capital are starting to take notice.
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AI drug development lands endorsements from pharma, VC

Oct. 16, 2017
By Brian Orelli
The use of artificial intelligence (AI) in drug development has increased substantially over the last few years. And both large pharmaceutical companies and venture capital are starting to take notice.
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View All Articles by Brian Orelli

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